Results 121 to 130 of about 416,729 (302)

Influencing Factors of Phosphorus Mobility and Retention in the Sediment of Three Typical Plateau Lakes

Toxics
The mechanisms driving changes in the stability of phosphorus (P) in sediments under lake ecosystem degradation remain poorly understood. This study investigated the P-binding forms in sediments from three plateau lakes with different trophic states in ...
Xue Wu, Yancai Wang, Lixin Jiao, Jia He, Hongbin Zhou, Zhengzheng Hao   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

The depth specific significiance, relative abundance and phylogeography of anaerobic ammonium oxidation (anammox) in marine and estuarine sediments [PDF]

, 2009
PhDThe availability of fixed forms of nitrogen is critical to the regulation of primary production. Until recently, denitrification (the sequential reduction of NO3 -, through NO2 - , to di-nitrogen gas) was recognised as the only significant pathway
Rooks, Christine
core   +2 more sources

Chemical Forms and Distribution Characteristics of Phosphorus in the Sediments of the Anning Phosphate Mining Area, Yunan Province

Yankuang ceshi
The chemical forms and content of phosphorus in sediments are the important basis for exploring bioavailability, migration, and transformation of phosphorus in sediments accurately.
Wei LIU, Jundong HU, Chenzi FAN, Yongbing LIU, Wenbo ZHAO, Chenghai LIU   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Impacts of LULC and climate change on runoff and sediment production for the Puyango-Tumbes basin (Ecuador-Peru)

Frontiers in Remote Sensing
Climate change will cause alterations in the hydrological cycle, a topic of great relevance to the scientific community due to its impacts on water resources.
Robinson Peña-Murillo, Waldo Lavado-Casimiro, Waldo Lavado-Casimiro, Luc Bourrel   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

RETRACTED: Assessing Mercury Contamination Levels in the Sediments of Two Pyrenean Lakes

Diversity
Mercury, a trace metal, is a persistent environmental pollutant that can be detected even in remote regions, including high-mountain lakes. This study examined mercury concentrations in the sediment of two lakes in the French Pyrenees, the Legunabens and
Cristian Yoel Quintero-Castañeda, Luis Roberto Hernández-Angulo, Daniel Tobón-Vélez, Anamaría Franco-Leyva, María Margarita Sierra-Carrillo   +4 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source