Microbial Influence on Carbon Storage and Trace Element Speciation in Restored and Natural Mangrove Sediments: A Synthesis of the Current Understanding. [PDF]
Uddin MM +6 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Characterization and quantification of microplastics in marine sediments of the Colombian Caribbean. [PDF]
Garzón-Rodríguez L +8 more
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Coexistence of Microplastics and Heavy Metals in Lake Sediments: Interaction Mechanisms and Complex Ecological Risks. [PDF]
Mi J, Lu J, Li Z, Jia Y.
europepmc +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Microplastics in Persian Gulf offshore sediments: Distribution, polymer composition, and ecological risk assessment. [PDF]
Amiri P, Shahbazi A, Mehdinia A.
europepmc +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Methane Gas Hydrate Morphology and its Effect on the Stiffness and Damping of some Sediments
Gas hydrates are ice–like compounds found in deep sea sediments and permafrosts. Concise detectionand quantification of natural methane gas hydrate deposits, will allow for a more robust assessmentof gas hydrate as a potential energy resource or natural ...
Rees, Emily V.L.
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