Results 101 to 110 of about 416,729 (302)
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openaire +2 more sources
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Fate of metals in coastal sediments of a Mediterranean flood-dominated system: An approach based on total and labile fractions [PDF]
The dynamics of sediment-bound metals (Cs, Cu, Ni, Pb, Ti and Zn) were studied off the Têt River (western Gulf of Lion), a typical Mediterranean coastal river punctuated by short and violent flash-floods.
Buscail, Roselyne +20 more
core +1 more source
A review of geophysical studies on the Mongolian Plateau
The Mongolian Plateau in Central Asia is an intracontinental tectonic system far from active plate boundaries. Despite its distance from these boundaries, the plateau is characterized by intense crustal deformation accompanied by voluminous Cenozoic ...
Lei Zhang +3 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Pore water chemistry and early diagenesis in sediments of Lake Rotorua, New Zealand [PDF]
To gain an understanding of the transfer of nutrients and trace elements from sediment pore waters to surface waters of eutrophic Lake Rotorua and the early diagenetic processes controlling the transfer, pore water chemistry in the sediments of Lake ...
Motion, Olivia Jane
core
Microbial Colonization of Minerals in Marine Sediments – Method Development and Ecological Significance [PDF]
Interactions between microorganisms and minerals significantly impact microbial diversity and geochemical cycles in diverse settings. However, methodological difficulty has inhibited past study of microbe–mineral interactions in fine-grained subsurface ...
Harrison, Benjamin Kimball
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Accumulation in bollom sediments and physiological state of the sturgeon of Volga-Caspian basin
There are defined the bottom sediments of the Caspian sea. Heir role in harlot metals accumulation and their impact on physiological state of the sturgeon fish.
V. F. Zaytsev +4 more
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Terrestrial organic matter biomarkers as tracers of Hg sources in lake sediments [PDF]
Terrestrial organic matter (TOM) plays a key role in mercury (Hg) dynamics between watersheds and lakes. In this study we attempts to determine the role of TOM source and quality and not only quantity, in the fate and transport of total Hg (T-Hg) to ...
Lucotte, Marc +2 more
core +1 more source

