GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Raw Marine Sediments in Concrete: Mechanical Performance, Durability, Environmental Release, and End-of-Life Behavior. [PDF]
Alassaad F +6 more
europepmc +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Total Mercury Levels in Sea Cucumbers Holothuria polii and Holothuria tubulosa and Sediments from Two Sites of Southern Italy. [PDF]
Di Lena G, Casini I, Caproni R.
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Compartment-Specific Differentiation of Bacterial Communities in the Sea Cucumber <i>Holothuria leucospilota</i> from the South China Sea. [PDF]
Chen X +7 more
europepmc +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Methane Gas Hydrate Morphology and its Effect on the Stiffness and Damping of some Sediments
Gas hydrates are ice–like compounds found in deep sea sediments and permafrosts. Concise detectionand quantification of natural methane gas hydrate deposits, will allow for a more robust assessmentof gas hydrate as a potential energy resource or natural ...
Rees, Emily V.L.
core
Effects of settled diatoms on autumn phytoplankton blooms in the Pacific Arctic: A process study of sediment resuspension in the Chukchi shelf. [PDF]
Fukai Y, Fujiwara A, Matsuno K.
europepmc +1 more source

