Results 111 to 120 of about 417,342 (302)

Influencing Factors of Phosphorus Mobility and Retention in the Sediment of Three Typical Plateau Lakes

Toxics
The mechanisms driving changes in the stability of phosphorus (P) in sediments under lake ecosystem degradation remain poorly understood. This study investigated the P-binding forms in sediments from three plateau lakes with different trophic states in ...
Xue Wu, Yancai Wang, Lixin Jiao, Jia He, Hongbin Zhou, Zhengzheng Hao   +5 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

The depth specific significiance, relative abundance and phylogeography of anaerobic ammonium oxidation (anammox) in marine and estuarine sediments [PDF]

, 2009
PhDThe availability of fixed forms of nitrogen is critical to the regulation of primary production. Until recently, denitrification (the sequential reduction of NO3 -, through NO2 - , to di-nitrogen gas) was recognised as the only significant pathway
Rooks, Christine
core   +2 more sources

Chemical Forms and Distribution Characteristics of Phosphorus in the Sediments of the Anning Phosphate Mining Area, Yunan Province

Yankuang ceshi
The chemical forms and content of phosphorus in sediments are the important basis for exploring bioavailability, migration, and transformation of phosphorus in sediments accurately.
Wei LIU, Jundong HU, Chenzi FAN, Yongbing LIU, Wenbo ZHAO, Chenghai LIU   +5 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Impacts of LULC and climate change on runoff and sediment production for the Puyango-Tumbes basin (Ecuador-Peru)

Frontiers in Remote Sensing
Climate change will cause alterations in the hydrological cycle, a topic of great relevance to the scientific community due to its impacts on water resources.
Robinson Peña-Murillo, Waldo Lavado-Casimiro, Waldo Lavado-Casimiro, Luc Bourrel   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

RETRACTED: Assessing Mercury Contamination Levels in the Sediments of Two Pyrenean Lakes

Diversity
Mercury, a trace metal, is a persistent environmental pollutant that can be detected even in remote regions, including high-mountain lakes. This study examined mercury concentrations in the sediment of two lakes in the French Pyrenees, the Legunabens and
Cristian Yoel Quintero-Castañeda, Luis Roberto Hernández-Angulo, Daniel Tobón-Vélez, Anamaría Franco-Leyva, María Margarita Sierra-Carrillo   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source