Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Characterization of the potential mercury contamination in the Apolobamba gold mining area, Bolivia Caracterización de la contaminación potencial por mercurio en el área minera de Apolobamba, Bolivia Caracterizaçao da potencial contaminaçao por mercúrio na área mineira de Apolobamba, Bolívia [PDF]
<p style="text-align: justify;">A large amount of Hg is used for gold extraction through the amalgamation process in the Apolobamba gold mining area located in the northwest part of La Paz, Bolivia.
José A. Acosta +6 more
doaj +1 more source
Relevance. Cleaning of reclamation channels is a very relevant event. The need to clean the canals and maintain them in working condition becomes obvious during the flood period, when it is necessary to remove excess water.
Kh. A. Abdulmazhidov
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Determination of the source location of the 2023 Jishishan M6.2 earthquake in Gansu Province
Based on the P-phase arrival time, we determined the source location of the Jishishan M6.2 earthquake with simulated annealing (SA) method, and quantitatively evaluated the reliability of the results using sample set statistical analysis method.
Zhiyuan Zhao +3 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Analysis on intelligent upgrading and transformation of seismic stations in Hebei Province
With the increasing number of earthquake stations and scaling up of unmanned stations, the traditional operation and maintenance mode of stations is facing various challenges such as frequent power supply, communication, and instrument failures.
Qin Tian, Kainan Chen, Pengjie Zhang
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Abstract River history is reflected in the nature of the sediments carried and deposited over time. Using examples drawn from around the world, this account illustrates how river sediments have been used to reconstruct past environmental changes at a variety of scales in time and space.
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

