Results 51 to 60 of about 417,252 (301)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Analysis on intelligent upgrading and transformation of seismic stations in Hebei Province

地震科学进展
With the increasing number of earthquake stations and scaling up of unmanned stations, the traditional operation and maintenance mode of stations is facing various challenges such as frequent power supply, communication, and instrument failures.
Qin Tian, Kainan Chen, Pengjie Zhang
doaj   +1 more source

River sediments [PDF]

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2012
Abstract River history is reflected in the nature of the sediments carried and deposited over time. Using examples drawn from around the world, this account illustrates how river sediments have been used to reconstruct past environmental changes at a variety of scales in time and space.
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Frequency dependence of acoustic waves in marine sediments [PDF]

, 2002
In situ techniques provide the most reliable method of examining the geoacoustical properties of marine sediments. In the past, individual in situ surveys have only been able to examine compressional waves over a maximum frequency range of 100 Hz to 50 ...
Robb, G., Dix, J.K., Best, A.I., Leighton, T.G., Riggs, J.S., Harris, A., Bull, J.M., White, P.R.   +7 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Analysis of the synchronous rise of water level in the Tangshan fault zone

Scientific Reports
Since 2019, a synchronous and abnormal upward trend in water levels has been observed in the Tangshan and Majiagou observation wells, located within the Tangshan fault zone, coinciding with three earthquakes of magnitude 4.0 or higher in the Tangshan ...
Jie Tang, Suxin Zhang, Dong Ma, Yan Wang, Lina Sun, Wenlou Luan   +5 more
doaj   +1 more source

Distribution and accumulation of heavy metals in sediments of the northern part of mangrove in Hara Biosphere Reserve, Qeshm Island (Persian Gulf)

Soil and Water Research, 2017
The mangrove of Hara Biosphere Reserve, stretching over 100 thousand hectares in the southern coast of Iran and in the northwest of Qeshm Island, belongs to the most important and largest mangroves in the Middle East.
Rezvan ZAREZADEH, Peyman REZAEE, Razyeh LAK, Mehdi MASOODI, Mansoor GHORBANI   +4 more
doaj   +1 more source

Sedimentation of Reservoirs [PDF]

, 2013
S waves are seismic body waves meaning they travel through the Earth's interior. Their velocity is slower thant that of P waves, and they are normally the second major phase to be observed on a seismorgram, and are therefore also referred to as secondary waves.
openaire   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source