Results 31 to 40 of about 1,263,730 (307)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Bridging quantum mechanics to liquid properties via a universal organic force field

Nature Communications
Molecular dynamics simulations are essential tools for unraveling atomic-level insights into the structure and behavior of condensed-phase systems. However, the universal and accurate prediction of macroscopic properties based on quantum mechanical ...
Tianze Zheng, Xingyuan Xu, Zhi Wang, Zhenze Yang, Yuanheng Wang, Xu Han, Lei Chen, Zhenliang Mu, Ziqing Zhang, Siyuan Liu, Sheng Gong, Kuang Yu, Wen Yan   +12 more
doaj   +1 more source

Intracellular Macrophage Infections with E. coli under Nitrosative Stress

Bio-Protocol, 2012
Escherichia coli (E. coli) produces disseminated infections of the urinary tract, blood, and central nervous system where it encounters professional phagocytes such as macrophages, which utilize reactive nitrogen intermediates (RNI) to arrest bacteria ...
Stacey Bateman, Patrick Seed
doaj   +1 more source

Managed pollination is a much better way of increasing productivity and essential oil content of dill seeds crop

Scientific Reports, 2022
Dill seeds (Anethum graveolens L.) is the most valuable medicinal seed spice crop of Apiaceae. It bears small yellow flowers in the form of umbels. Being a cross-pollinated crop, floral visitors play vital role in pollination and seed sets.
Narottam Kumar Meena, Ram Swaroop Meena, Ravindra Singh, Arvind Kumar Verma, Sharda Choudhary, Balraj Singh, Ram Dayal Meena, Ravi Y, Murlidhar Meena   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Wheat and barley seed system in Syria: farmers' varietal perceptions, seed sources and seed management [PDF]

, 2011
A total of 206 wheat and 200 barley farmers were interviewed in northeastern Syria to understand farmer perceptions and practice relating to modern varieties, seed sources and seed quality. Wheat farmers had better awareness and grew modern varieties (87%
Gastel, A.J.G., van, Struik, P.C., Bishaw, Z.   +2 more
core  

Development of a Food Security Indicator Framework in British Columbia

Journal of Agriculture, Food Systems, and Community Development, 2019
Food security is complex in both content and governance, making it difficult to measure and monitor. In 2016, the Population and Public Health Program of the British Columbia Centre for Disease Control, Provincial Health Services Authority, sought to ...
Barbara Seed, Melanie Kurrein
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source