Results 141 to 150 of about 515,814 (317)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
An Analysis of Pricing in the U.S. Cotton Seed Market
The purpose of the research in this paper is to investigate the impact of differentiated vertical strategies by agricultural biotechnology firms in the U.S. cottonseed market.
Stiegert, Kyle W. +2 more
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Seed provision and dryland crops in the semiarid regions of Eastern Kenya: [PDF]
"Over the last two decades, several seed-related programs have been initiated in eastern Kenya to improve farmers' access to quality seeds of dryland cereals and legumes. They are provided during two occasions, regular and emergency times. But very often,
Nagarajan, Latha +3 more
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Loss of Lateral suppressor gene is associated with evolution of root nodule symbiosis in Leguminosae
Genome BiologyBackground Root nodule symbiosis (RNS) is a fascinating evolutionary event. Given that limited genes conferring the evolution of RNS in Leguminosae have been functionally validated, the genetic basis of the evolution of RNS remains largely unknown ...
Tengfei Liu +16 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Adoption of Improved Maize Seed by Smallholder Farmers in Mozambique
The objective of this paper is to investigate factors influencing the adoption of improved maize seed by smallholder farmers in Mozambique. The data used in this study were obtained from a national random sample of 4,908 smallholder farmers conducted by ...
Christy, Ralph D. +2 more
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Correlation Analysis for Seed Yield and Its Contributing Traits in Isabgol Genotypes
, 2017 The present investigation was carried out at main experiment station Horticulture, Department of Horticulture, NDUA&T, Kumarganj, Faizabad (U.P.) to study the correlation analysis for seed yield and its contributing traits on 42 genotypes of Isabgol. The
Deen Dayal Singh +9 more
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Smallholder potato farmers in Ethiopia do not realize the theoretical yield potential of the crop because they do not benefit from the advantages of using quality seed potato of improved varieties.
Lemma Tessema +2 more
core +1 more source