A century-long record of plant evolution reconstructed from a coastal marsh seed bank. [PDF]
Blum MJ +5 more
europepmc +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Response of the germinable soil seed bank of temperate Leymus chinensis meadows to mowing regimes. [PDF]
Zhang Z +7 more
europepmc +1 more source
Effect of Snowmelt on Groundwater Bacterial Community Composition and Potential Role of Surface Environments as Microbial Seed Bank in Two Distinct Aquifers from the Region of Quebec, Canada. [PDF]
Villeneuve K +2 more
europepmc +1 more source
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang +12 more
wiley +1 more source
Changes with time post-restoration in the relationships between soil seed bank and aboveground vegetation in a reclaimed open-pit coal mine. [PDF]
Liu Y +5 more
europepmc +1 more source
Comparative whole-genome and proteomics analyses of the next seed bank and the original master seed bank of MucoRice-CTB 51A line, a rice-based oral cholera vaccine. [PDF]
Sasou A +15 more
europepmc +1 more source
A bioinstructive injectable hydrogel enables sustained release of stromal cell–derived factor‐1 alpha (SDF‐1α) and stable retention of laminin through ionic and hydrophobic interactions. This dual‐signaling matrix promotes endogenous stem cell recruitment and training, supports angiogenesis, and enhances intrinsic regenerative processes in ischemic ...
Yurim Kim, Young‐Min Kim
wiley +1 more source
Orchid seeds are not always short lived in a conventional seed bank! [PDF]
Francisqueti AM +6 more
europepmc +1 more source
Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun +8 more
wiley +1 more source

