Results 181 to 190 of about 405,879 (301)

Effect of Snowmelt on Groundwater Bacterial Community Composition and Potential Role of Surface Environments as Microbial Seed Bank in Two Distinct Aquifers from the Region of Quebec, Canada. [PDF]

Microorganisms, 2023
Villeneuve K, Turcotte-Blais V, Lazar CS.   +2 more
europepmc   +1 more source

Machine Learning‐Guided Engineering of Protein Phase Separation Properties in Immune Regulation

Advanced Science, EarlyView.
PScalpel, a machine learning model integrating protein structure extraction, graph contrastive learning, and a genetic algorithm, guides the engineering of protein phase separation ability. It adopts transfer learning methods to provide predictive recommendations for protein phase separation ability changes through single amino acid mutations in a ...
Chenqiu Zhang, Jia Wang, Zhe Wang, Liyan Zhu, Sihui Cai, Luzhi Zhan, Haorui Liang, Yaoxing Wu, Jianqiang Li, Jun Cui   +9 more
wiley   +1 more source

Orchid seeds are not always short lived in a conventional seed bank! [PDF]

Ann Bot
Francisqueti AM, Marin RR, Hengling MM, Hosomi ST, Pritchard HW, Custódio CC, Machado-Neto NB.   +6 more
europepmc   +1 more source

Seed bank persistence of a South American cordgrass in invaded northern Atlantic and Pacific Coast estuaries. [PDF]

AoB Plants, 2021
Abbas AM, Pickart AJ, Goldsmith LM, Davenport DN, Newby B, Muñoz-Rodríguez AF, Grewell BJ, Castillo JM.   +7 more
europepmc   +1 more source

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma, Yang Li, Shen Lin, Feifan Chu, Gaozhan Ren, Yinhui Mao, Mingzhi Wu, Yuning Ma, Qiwei Ji, Zujie Chen, Jinzhong Ji, Mingxin Sun, Yongpeng Xu, Xiaoli Sun, Longguang Tang, Hao Zhou   +15 more
wiley   +1 more source

Effects of Acmella radicans Invasion on Soil Seed Bank Community Characteristics in Different Habitats. [PDF]

Plants (Basel)
Wu X, Yang K, Zheng F, Xu G, Fan Z, Clements DR, Yang Y, Yang S, Jin G, Zhang F, Shen S.   +10 more
europepmc   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Fencing vs. Grazing: Divergent Effects on Soil Seed Bank Structure and Grassland Recovery Pathways in Northern Tibetan Alpine Grasslands. [PDF]

Plants (Basel)
Xie Y, Liu Y, Li W, Zhao N, Li X, Chen Y, Lai G, Lou X, Wang X, Wei X.   +9 more
europepmc   +1 more source

Seed Dormancy and Soil Seed Bank of the Two Alpine Primula Species in the Hengduan Mountains of Southwest China. [PDF]

Front Plant Sci, 2021
Peng DL, Yang LE, Yang J, Li ZM.
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source