Results 71 to 80 of about 35,401 (292)

Vicia faba germplasm collection in eastern Transylvania

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 1987
Vicia faba accessions have been collected from peasants in Eastern Transylvania in the period 1981-1985. The crop is cultivated mostly in the eastern part of Harghita District.
P. PALFALVI
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Seed colour and linolenic acid effects on agronomic traits in flax

open access: yes, 1999
Solin flax (Linum usitatissimum L.) is an edible-oil crop that must have less than 5% linolenic acid in its seed oil and a yellow seed coat. Seed vigour of solin is often lower than that of brown-seeded linseed flax and this lower seed vigour has been ...
G. Saeidi, G. G. Rowland
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Seed colour and post-fire bird predation in a Mediterranean pine forest. [PDF]

open access: yes, 2004
In a Pinus halepensis Mill. forest, a field experiment was designed to evaluate post-fire seed predation as affected by combinations of seed colour and soil substrates: light grey and black seeds combined with light grey ash, dark grey ash and pale brown
D'ALESSANDRO, Carmela Miriam   +5 more
core   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Inheritance study of qualitative and quantitative characters in cowpea varieties (Vigna unguiculata (L.) Walp)

open access: yesElectronic Journal of Plant Breeding, 2016
Two parents namely Konkan Safed and Konkan Sadabahar were used to study inheritance of four qualitative characters (i.e., growth habit, flower colour, seed coat colour and seed coat colour pattern) and four quantitative characters i.e.
Tejashree S. Lachyan   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Seed Characteristics Diversity in Sponge Gourd (Luffa aegyptiaca Mill.) Germplasms from Hatay Region in Turkey

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, 2018
The objective of this study was to evaluate seed characteristics of sponge gourd, to establish a core collection of sponge gourd with the germplasm collected throughout the Hatay region.
Kazım MAVİ   +3 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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