Results 81 to 90 of about 192,388 (308)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Pathogenicity and horizontal transmission of Beauveria bassiana and Metarhizium anisopliae isolates used against Sahlbergella singularis, ccoa pest in Cameroon [PDF]
, 2017 The brown cocoa mirid, Sahlbergella singularis (Heteroptera: Miridae) has been named the most economically important insect pest of cocoa across West African and it is capable to cause yield loss of about 30 to 70%.
Bagny-Beilhe, Leïla +3 more
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How the shapes of seeds can influence pathology
Neurobiology of Disease, 2018 It is widely accepted that the loss of function of different cellular proteins following their aggregation into highly stable aggregates or the gain of pathologic function of the resulting macromolecular assemblies or both processes are tightly associated to distinct debilitating neurodegenerative diseases such as Alzheimer's, Parkinson's, Creutzfeldt ...
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Selection for resistance against root pathogens in a pea composite cross [PDF]
, 2007 The possibility of improving resistance in pea against the root pathogen Aphanomyces euteiches using composite cross as a breeding and selection method was examined.
Bødker, Lars +4 more
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Strategies to control late blight in potatoes in Europe [PDF]
, 2009 In Europe an aggressive genetically diverse population of potato late blight is present which regularly causes problems in all potato growing regions.
Evenhuis, A. +2 more
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Actividad fungicida/fungistática in vitro del fosfito de manganeso contra hongos patógenos habitantes del suelo con soja [PDF]
, 2017 Las pudriciones de raíz y tallo (PRYT) en el cultivo de soja causadas por patógenos habitantes del suelo son enfermedades comúnmente encontradas en campos de soja y son una de las causas más importantes de pérdidas económicas. La sensibilidad micelial de
Carmona, Marcelo Anibal +6 more
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Distribution and incidence of viruses in Irish seed potato crops [PDF]
, 2015 peer-reviewedVirus diseases are of key importance in potato production and in particular for the production of disease-free potato seed. However, there is little known about the frequency and distribution of potato virus diseases in Ireland.
Bonner, D. +6 more
core +1 more source
Pathological Study of Retinoblastoma treated by Radon Seeds and Radium Disks [PDF]
British Journal of Ophthalmology, 1952 FIRST, I thank you most sincerely for the great honor you have done me in inviting me to give this lecture in memory of the late Charles H. May. Charles H. May came to New York at the age of 4, and in this great city his work as a famous teacher, a skillful surgeon, and a man of absolute integrity of character and high ethical standards justifiably ...
openaire +4 more sources