Results 131 to 140 of about 282,702 (308)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Effect of different Bradyrhizobium japonicum inoculants on physiological and agronomic traits of soybean (Glycine max (L.) Merr.) associated with different expression of nodulation genes

BMC Plant Biology
The aim of this work was to check the effects of five Bradyrhizobium japonicum inoculants from different producers on growth, photochemical efficiency, nitrate reductase activity, amount of hydrogen peroxide, activity of catalase, non-specific peroxidase,
Anna Szczerba, Agnieszka Płażek, Przemysław Kopeć, Magdalena Wójcik-Jagła, Franciszek Dubert   +4 more
doaj   +1 more source

Conservation seed physiology of the ciénega endemic, Eryngium sparganophyllum (Apiaceae). [PDF]

Conserv Physiol, 2020
Wolkis D, Blackwell S, Villanueva SK.
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Alterations in carbon and nitrogen metabolism under phenylalanine ammonia-lyase inhibition in winter triticale seedlings

Scientific Reports
This study aimed to assess the impact of phenylalanine ammonia-lyase (PAL) inhibition on the carbon and nitrogen metabolism of winter triticale seedlings using 4-hydroxybenzoic acid hydrazide (HBH, 10⁻³ M), with particular attention to sugar accumulation
Katarzyna Hura, Michał Dziurka, Tomasz Hura, Andrzej Zieliński   +3 more
doaj   +1 more source

Testes de deterioração controlada e envelhecimento acelerado para avaliação do vigor em nabo forrageiro

Revista Ciência Agronômica
O objetivo do trabalho foi verificar a eficiência de diferentes procedimentos para condução dos testes de envelhecimento acelerado e deterioração controlada visando avaliação da qualidade fisiológica de sementes de nabo forrageiro (Raphanus Sativus L ...
Camila Santos Barros de Morais, Claudia Antonia Vieira Rossetto   +1 more
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Using the optimal seed germination temperature approach to determine the potential distribution of Inga jinicuil in Mexico under climate change scenarios

Scientific Reports
Inga jinicuil is used extensively in shade coffee farms in Mexico, a diversified agroforestry system providing important environmental goods and services. However, its recalcitrant seeds represent an important barrier to its propagation.
Salvador Sampayo-Maldonado, Daniel Cabrera-Santos, Patricia Dávila-Aranda, Norma Isela Rodríguez-Arévalo, Alma Orozco-Segovia, Maraeva Gianella, Elizabeth Bell, Michael Way, Robert H. Manson, Gabina S. Quintas, Cesar M. Flores-Ortíz, Tiziana Ulian   +11 more
doaj   +1 more source