Results 101 to 110 of about 1,170,351 (346)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Arabidopsis seeds priming v1

, 2022
The treated seeds can grow in medium or bulk soil to determine the impact of novel materials on plants.
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Effect of priming on growth, biochemical parameters and mineral composition of different cultivars of coriander (Coriandrum sativum L.) under salt stress [PDF]

, 2014
At Higher Institute of Agriculture of Chott Mariem, Sousse, Tunisia, this study was conducted to evaluate the interactive effect of salinity and seed priming on coriander.
Belanger Andre, Ben Fredj Meriem, Hannachi Cherif, Mehwachi Tijani, Zhani Kaouther   +4 more
core  

Application of Moringa Leaf Extract as a Seed Priming Agent Enhances Growth and Physiological Attributes of Rice Seedlings Cultivated under Water Deficit Regime

Plants, 2022
Population growth, food shortages, climate change and water scarcity are some of the frightening challenges being confronted in today’s world. Water deficit or drought stress has been considered a severe limitation for the productivity of rice, a widely ...
Shahbaz Khan, D. Ibrar, S. Bashir, Nabila Rashid, Z. Hasnain, M. Nawaz, A. Al-ghamdi, M. Elshikh, H. Dvořáčková, Jan Dvořáček   +9 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Invigorasi Benih untuk Memperbaiki Perkecambahan Kacang Panjang (Vigna Unguiculata Hask. Ssp. Sesquipedalis) pada Cekaman Salinitas [PDF]

, 2008
The objective of this research was to study the influence of invigoration on yard-long bean seed germination under salinity stress. The research was conducted at Seed Science and Technology Laboratory, Department of Agronomy IPB from September to ...
Erinnovita, E. (Erinnovita), Guntoro, D. (Dwi), Sari, M. (Maryati)   +2 more
core  

Proteomic Analysis of Arabidopsis Seed Germination and Priming [PDF]

Plant Physiology, 2001
Abstract To better understand seed germination, a complex developmental process, we developed a proteome analysis of the model plant Arabidopsis for which complete genome sequence is now available. Among about 1,300 total seed proteins resolved in two-dimensional gels, changes in the abundance (up- and down-regulation) of 74 proteins ...
Gallardo, Karine, Job, C., Groot, S.P., Puype, M., Demol, H., Vandekerckhove, J., Job, D.   +6 more
openaire   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Jasmonic acid-dependent regulation of seed dormancy following maternal herbivory in Arabidopsis [PDF]

, 2017
Maternal experience of abiotic environmental factors such as temperature and light are well known to control seed dormancy in many plant species. Maternal biotic stress alters offspring defence phenotypes, but whether it also affects seed dormancy ...
Agrawal, Agrawal, Anderson, Anuja Dave, Conrath, Dave, Dave, Dawn Worrall, Donohue, Donohue, Ellis, Fabian E. Vaistij, Fan, Fenner, Filip Kaminski, Geoff H. Holroyd, Graeber, He, Holdsworth, Holeski, Holeski, Howe, Ian A. Graham, Jonathan G. Wells, Kendall, Koo, Linkies, Luna, Martel, Michael R. Roberts, Miquel, Mousseau, Pieterse, Prashant Singh, Preston, Rasmann, Roach, Robert-Seilaniantz, Ruggiero, Staswick, Sultan, Taki, Tricker, Tricker, Vu, Wasternack, Wilen, Worrall   +47 more
core   +2 more sources