Results 71 to 80 of about 56,614 (300)

Mutations in UDP-Glucose:Sterol Glucosyltransferase in Arabidopsis Cause Transparent Testa Phenotype and Suberization Defect in Seeds [PDF]

, 2009
In higher plants, the most abundant sterol derivatives are steryl glycosides (SGs) and acyl SGs. Arabidopsis (Arabidopsis thaliana) contains two genes, UGT80A2 and UGT80B1, that encode UDP-Glc:sterol glycosyltransferases, enzymes that catalyze the ...
Auer, Manfred, Beisson, Fred, Bischoff, Volker, Bouvier-Navé, Pierrette, Carroll, Andrew, DeBolt, Seth, Hematy, Kian, Li, Yonghua, Milne, Jennifer, Nair, Meera, Schaller, Hubert, Scheible, Wolf-Rüdiger, Schrick, Kathrin, Somerville, Chris, Zemla, Marcin   +14 more
core   +5 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Invigorasi Benih untuk Memperbaiki Perkecambahan Kacang Panjang (Vigna Unguiculata Hask. Ssp. Sesquipedalis) pada Cekaman Salinitas [PDF]

, 2008
The objective of this research was to study the influence of invigoration on yard-long bean seed germination under salinity stress. The research was conducted at Seed Science and Technology Laboratory, Department of Agronomy IPB from September to ...
Erinnovita, E. (Erinnovita), Guntoro, D. (Dwi), Sari, M. (Maryati)   +2 more
core  

Jasmonic acid-dependent regulation of seed dormancy following maternal herbivory in Arabidopsis [PDF]

, 2017
Maternal experience of abiotic environmental factors such as temperature and light are well known to control seed dormancy in many plant species. Maternal biotic stress alters offspring defence phenotypes, but whether it also affects seed dormancy ...
Agrawal, Agrawal, Anderson, Anuja Dave, Conrath, Dave, Dave, Dawn Worrall, Donohue, Donohue, Ellis, Fabian E. Vaistij, Fan, Fenner, Filip Kaminski, Geoff H. Holroyd, Graeber, He, Holdsworth, Holeski, Holeski, Howe, Ian A. Graham, Jonathan G. Wells, Kendall, Koo, Linkies, Luna, Martel, Michael R. Roberts, Miquel, Mousseau, Pieterse, Prashant Singh, Preston, Rasmann, Roach, Robert-Seilaniantz, Ruggiero, Staswick, Sultan, Taki, Tricker, Tricker, Vu, Wasternack, Wilen, Worrall   +47 more
core   +2 more sources

Proteomic Analysis of Arabidopsis Seed Germination and Priming [PDF]

Plant Physiology, 2001
Abstract To better understand seed germination, a complex developmental process, we developed a proteome analysis of the model plant Arabidopsis for which complete genome sequence is now available. Among about 1,300 total seed proteins resolved in two-dimensional gels, changes in the abundance (up- and down-regulation) of 74 proteins ...
Gallardo, Karine, Job, C., Groot, S.P., Puype, M., Demol, H., Vandekerckhove, J., Job, D.   +6 more
openaire   +3 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Priming Benih Padi (Oryza Sativa L.) dengan Zn untuk Meningkatkan Vigor Bibit pada Cekaman Terendam [PDF]

, 2016
Seed priming has been widely used to improve seedling vigor of several crops such as corn, wheat, and rice. Seed priming with zinc to increase seedling tolerance on submergence stress had never been evaluated.
Hasmeda, M. (Mery), Sulaiman, S. (Sulaiman), Suwignyo, R. A. (Rujito), Wijaya, A. (Andi)   +3 more
core   +3 more sources

Maintaining Onion Seed Quality during Storage Through Seed Priming

Agricultural Reviews, 2022
Background: Seed is an important component and the quality seed plays a crucial role in agricultural production as well as in the national economy. Availability of viable and vigorous seeds at the planting time is important. Onion seeds have a short life span among the vegetable crops and lose viability rapidly after harvest.
V.P.S. Panghal, Axay Bhuker, D.S. Duhan, Amit Kumar   +3 more
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source