Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Targeted Reduction of Specific Antinutritional and Allergen-Associated Proteins to Advance Soybean Seed Quality. [PDF]
Krishnan HB, Kim W, Kim S, Nguyen TT.
europepmc +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Decoding the genetic architecture of seed quality traits in mungbean through quantitative trait loci mapping. [PDF]
Ren C +8 more
europepmc +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Contrasting effects of mineral, farmyard manure, and integrated fertilization on soybean productivity, seed quality, and soil biochemical properties. [PDF]
Ramazanoglu E +8 more
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
The dynamic of the controversy around the brussel pedestrian
La dynamique de la controverse apparue autour du projet de piétonisation des boulevards centraux de la Ville de Bruxelles est relue à travers la théorie de l’acteur réseau (Callon &Latour 1986) .
Charlery de la Masselière, Madeleine +5 more
core
Genome-Wide Identification of the WD40 Gene Family and Functional Analysis of a Candidate Gene Regulating Seed Quality in Soybean. [PDF]
Chen H +9 more
europepmc +1 more source

