Results 91 to 100 of about 8,298,845 (325)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Is it possible to check micro ginning fiber quality preservation performance using reference seed-cotton materials? [PDF]

open access: yes, 2016
In sub-Saharian countries, simple micro-gin, without seed-cotton cleaner nor lint-cleaner, is often used as a reference device for characterizing the performance of industrial gin plants for fiber quality preservation.
Gourlot, Jean-Paul   +3 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Modelling the spreading of wilding conifers [PDF]

open access: yes, 2004
In many parts of the Canterbury high country, conifer seeds are spreading on the wind from exisiting plantations and shelterbelts, leading to a serious weed problem.
North, Heather, Roberts, Mick
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Pollination Studies on Both Floret and Capitulum Levels in an Oil Seed Crop, Guizotia abyssinica (L.f.) Cass.

open access: yesJournal of Apicultural Science, 2021
Niger, Guizotia abyssinica (L.f.), is an important oilseed crop widely grown in Ethiopia and India, but poor pollination is one of the major constraints in achieving the yield potential of the crop.
Veereshkumar   +3 more
doaj   +1 more source

Assessing the Genotypic Differences for Seed Set and Seed Abortion in Tomato Genotypes [PDF]

open access: yes, 2009
Tomato (_Lycopersicon esculentum_ Mill.) is one of the most popular fruit vegetable around the world. Seed abortion where in only a small proportion of ovules in an ovary develops into matured seeds, is a wide spread phenomenon in multi-ovulated species.
Chalapathy K. Reddy   +2 more
core   +1 more source

Evaluating the Potential of Using 5-Azacytidine as an Epimutagen [PDF]

open access: yes, 2000
A number of early flowering lines were induced when 5-azacytidine was applied to germinating flax (Linum usitatissimum L.) seed. The genetics of these lines indicate that the induced changes are epigenetic and probably result from demethylation of the ...
Durrant A.   +11 more
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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