Results 101 to 110 of about 8,298,845 (325)
Acta Societatis Botanicorum Poloniae, 2014 Although the knowledge of pollination systems of rare and threatened species is one of the principles for development of optimal conservation and management strategies, the data about their pollination requirements are scarce or incomplete.
Bożena Denisow +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Acta Agrobotanica, 2017 Polemonium caeruleum (Polemoniaceae) represents a very interesting system of compatibility transition. Studies of its biological and ecological properties in the context of the breeding system of various populations may help to understand the ...
Beata Ostrowiecka +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Seed production in dianthus (Dianthus plumaris L.) : a thesis presented in partial fulfilment of the requirement for the degree of Master of Applied Science in Seed Technology at Massey University, Palmerston North, New Zealand [PDF]
, 1998 Stigma receptivity, method of pollination and seed production under glass house and field conditions of ten Hammett Dianthus (Dianthus plumaris L.) cultivars were investigated in this study.
Hewage, Nandana Pushpakumara
core
Combining Traditional Marketing and Viral Marketing with Amphibious Influence Maximization
, 2015 In this paper, we propose the amphibious influence maximization (AIM) model that combines traditional marketing via content providers and viral marketing to consumers in social networks in a single framework.
Chen, Wei +3 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source