Results 131 to 140 of about 8,298,845 (325)
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Pollinators are well known to provide key ecosystem. Animal pollinators are thought to contribute between 15 and 30% of global food production and bees are recognized to be the most important taxon.
TRI ATMOWIDI +2 more
doaj
Periodically taken photographs reveal the effect of pollinator insects on seed set in lotus flowers. [PDF]
Nagai M +6 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Drought-Induced Changes in The Flowering Capacity, Anthesis Quality and Seed Set in Rice (Oryza sativa L.). [PDF]
Salleh MS +6 more
europepmc +1 more source
Organic Heirloom Spring Wheat Seeding Rate Trial [PDF]
University of Vermont Extension began its heirloom spring wheat project in 2007 to determine whether heirloom varieties developed before 1950 could thrive in Vermont’s climate.
Calderwood, Lily +5 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Effect of Prices, Traits and Market Structure on Corn Seeding Density [PDF]
Recent agronomic research finds that economically optimal seeding densities have likely increased for many Midwestern corn farmers as a result of genetic improvements including new GM traits such as Bt corn and herbicide tolerance.
Lauer, Joseph G. +3 more
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Callianthe sellowiana is a high‐altitude species endemic to the Atlantic Forest that exhibits floral traits overlapping between ornithophily (hummingbird pollination) and chiropterophily (bat pollination), with highly variable flower color and shape and ...
Isis Paglia +2 more
doaj +1 more source

