Results 131 to 140 of about 8,298,845 (325)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

POLLINATION EFFECTIVENESS OF APIS CERANA FABRICUS AND APIS MELLIFERA LINNAEUS (HYMENOPTERA: APIDAE) IN JATROPHA CURCAS L. (EUPHORBIACEAE)

open access: yesBiotropia: The Southeast Asian Journal of Tropical Biology, 2008
Pollinators are well known to provide key ecosystem. Animal pollinators are thought to contribute between 15 and 30% of global food production and bees are recognized to be the most important taxon.
TRI ATMOWIDI   +2 more
doaj  

Periodically taken photographs reveal the effect of pollinator insects on seed set in lotus flowers. [PDF]

open access: yesSci Rep, 2022
Nagai M   +6 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Drought-Induced Changes in The Flowering Capacity, Anthesis Quality and Seed Set in Rice (Oryza sativa L.). [PDF]

open access: yesTrop Life Sci Res, 2022
Salleh MS   +6 more
europepmc   +1 more source

Organic Heirloom Spring Wheat Seeding Rate Trial [PDF]

open access: yes, 2015
University of Vermont Extension began its heirloom spring wheat project in 2007 to determine whether heirloom varieties developed before 1950 could thrive in Vermont’s climate.
Calderwood, Lily   +5 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Effect of Prices, Traits and Market Structure on Corn Seeding Density [PDF]

open access: yes
Recent agronomic research finds that economically optimal seeding densities have likely increased for many Midwestern corn farmers as a result of genetic improvements including new GM traits such as Bt corn and herbicide tolerance.
Lauer, Joseph G.   +3 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Mixed Bat‐Hummingbird Pollination Assures Reproductive Success in a Highly Variable Upper Montane Species

open access: yesEcology and Evolution
Callianthe sellowiana is a high‐altitude species endemic to the Atlantic Forest that exhibits floral traits overlapping between ornithophily (hummingbird pollination) and chiropterophily (bat pollination), with highly variable flower color and shape and ...
Isis Paglia   +2 more
doaj   +1 more source

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