Results 141 to 150 of about 4,885,715 (249)

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Molecular Mapping and CRISPR/Cas9 Validation Reveal That <i>SlVQ10</i> Regulates Seed Size in Tomato. [PDF]

Plants (Basel)
Sun T, Chen L, Zhu X, Pei T, Wang Y, Liu C, Zhang H, Li D, Zhao T, Xu X.   +9 more
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Genetic loci underlying seed size and yield-related traits in cowpea. [PDF]

Front Plant Sci
Iro Sodo AM, Fatokun C, Olasanmi B, Ongom PO, Dieng I, Boukar O.   +5 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Seed size and genotype effects on maize (Zea mays L.) yield under different technology levels

, 2014
Final plant population in maize crop was used as a basis to identify the technology level of a given farmer. Final population of 50,000 plants/hectare was considered as an indication of a high technology level farmer; 35,000 of a medium, and 20,000 of a ...
De Carvalho, N. M., Martinelli, A.
core  

The IKU2/RLK7-MAPK-MINI3 signaling module controls endosperm cellularization timing to determine seed size in Arabidopsis. [PDF]

J Integr Plant Biol
Ni M, Qian Y, Nong T, Mou W, Liu N, Yang, Li D, Shou H, Xu J.   +8 more
europepmc   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Sources, Replacement and Management of Paddy Seed by Farmers in Punjab [PDF]

The study has reported different sources of paddy seed, seed replacement rate of paddy growers, and management of paddy seed by the farmers in two selected districts of Punjab.
Sidhu, M.S., Verma, Sangeeta
core  

Correction: Molecular tagging of seed size using MITE markers in an induced large seed mutant with higher cotyledon cell size in groundnut. [PDF]

3 Biotech
Bhad PG, Mondal S, Badigannavar AM.
europepmc   +1 more source