Results 111 to 120 of about 500,532 (311)

Organic Spring Wheat Seeding Rate Trial Report [PDF]

, 2013
Throughout Vermont and the Northeast, the demand for local organically grown wheat continues to rise. Due to this demand, there has been a renewed interest by producers to add wheat into their crop rotations.
Burke, Conner, Cummings, Erica, Darby, Heather, Harwood, Hannah, Monahan, Susan   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Research on an effective artificial regeneration method for selected commercially important coniferous tree species on a large sanitation cut site situated in the Javorníky Mts., Western Carpathians

Journal of Forest Science
In response to the decline of Central European spruce monocultures driven by various factors, the Demonstration Object of Reconstruction of Spruce Forests (DORS) was established in Husárik locality, Javorníky Mts., northwestern Slovakia.
Martin Belko, Anna Tučeková, Roman Longauer, Valéria Longauerová, Vladimír Mačejovský, Ivan Horvát   +5 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Tillage Radish Seeding Rate Trial [PDF]

, 2014
Tillage radishes are being utilized by farmers as a new cover crop for their unique characteristics. Tillage radishes are quick at scavenging nitrogen, provide good ground cover, and break down very quickly in the spring to make way for spring planting ...
Cummings, Erica, Darby, Heather, Monahan, Susan, Post, Julian, Ziegler, Sara   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Winterhardiness and Agronomic Performance of Wildryes (Elymus species) Compared With Other Grasses in Alaska, and Responses of Siberian Wildrye to Management Practices [PDF]

, 1993
This report summarizes eight field experiments involving both native and introduced wildrye grasses (Elymus species) conducted over a span of several years at the University of Alaska’s Matanuska Research Farm (61.6oN) near Palmer in southcentral ...
Klebesadel, Leslie J.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Soft X-ray seeding studies for the SLAC Linac Coherent Light Source II [PDF]

, 2019
We present the results from studies of soft X-ray seeding options for the LCLS-II X-ray free electron laser (FEL) at SLAC. The LCLS-II will use superconducting accelerator technology to produce X-ray pulses at up to 1 MHz repetition rate using 4 GeV ...
Coffee, R, Dakovski, G, Fawley, WM, Hastings, J, Hemsing, E, Huang, Z, Marcus, G, Penn, G, Ratner, D, Raubenheimer, T, Schoenlein, RW   +10 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source