Results 141 to 150 of about 327,495 (306)
Compressed sensing is a signal processing method that acquires data directly in a compressed form. This allows one to make less measurements than what was considered necessary to record a signal, enabling faster or more precise measurement protocols in a
Bayati M Lelarge M Montanari A +31 more
core +4 more sources
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Improving Siberian larch seed germination rates
The flotation technique was used to segregate non-viable from viable Siberian larch (Larix Sibirica Ledeb.) seeds using water as the floating media. The non-viable seeds floated while the viable ones sank. Without stratification, the average percent germination of the floating and sunken seeds were 4.2% and 71.0% respectively.
openaire +3 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Improving Wildflower Longevity in Roadside Seeding Areas [PDF]
Re-vegetation efforts on bare roadsides of newly-constructed highways are primarily focused on the stabilization of soil to reduce rates of erosion. The Nebraska Department of Transportation (NDOT) seeds roadsides with a diverse mixture of grasses and ...
Schacht, Walter +2 more
core +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The effect of seed quality on winter common wheat productivity is well known. The current paper has presented the results of a field trial to study the effect of seeding rates and the fractional composition of seeds on the productivity of the winter ...
Yu. G. Skvortsova +2 more
doaj +1 more source

