Results 191 to 200 of about 2,805,876 (348)
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock +8 more
wiley +1 more source
The aerobic inhibition of glycolysis in pea-seed extracts and its possible relationship to the Pasteur effect [PDF]
, 1959 M.D. Hatch, John F. Turner
openalex +1 more source
Advanced Biology, EarlyView.Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe +4 more
wiley +1 more source
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
Advanced Biology, EarlyView.This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer +8 more
wiley +1 more source
Acoustophoretic system for seed separation on conveyor belts. [PDF]
Nat CommunHardwick J, Morgan Z, Hirayama R.
europepmc +1 more source
On the Distribution and Organic Contents of the “Ludlow Bone Bed” in the Districts of Woolhope and May Hill. With a Note on the Seed-like Bodies found in it [PDF]
Hugh Edwin Strickland +1 more
openalex +1 more source