Results 71 to 80 of about 54,512,962 (278)

Seeing conspiracy theorists everywhere as a conspiracy paradox

open access: yesCommunications Psychology
Concerns about the consequences of conspiracy theories have grown. Widespread belief in unfounded conspiracy theories is only one associated risk. Conversely, academics mustn’t commit the reverse error, in adopting a Protective Conspiracy Framing and ...
Nicolas Vermeulen
doaj   +1 more source

Seeing (not) seeing: the phenomenology of deviant standpoint as a function of gender and class in Paulinus of Nola, Poems 18

open access: yesEugesta, 2018
Identifying an allusion to classical Greco-Roman poetry in a monologue (or prosopopoeia) of a cowherd by the fourth century Latin poet, Paulinus of Nola (c. 18.276-80), this article explains the emergence of the category of labor as a response to a
Alex Dressler
doaj   +1 more source

Is There an Internal Link between Seeing a Human and Seeing One to Whom Moral Consideration Is Due?

open access: yes
Is There an Internal Link between Seeing a Human and Seeing One to Whom Moral Consideration Is ...
Ariso Salgado, José María
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Seeing in: Two-fold, three-fold? [PDF]

open access: yes, 2016
Taking Richard Wollheim’s theory that seeing pictures is a two-fold experience of perception, (between the marked surface of the physical object and something depicted in its surface), this paper analyses my recent practice of creating artworks that ...
Robinson, C.
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Education of Senses in Free Time: seeing as entertainment

open access: yesEducação & Realidade, 2020
Nowadays we are increasingly subordinated by the excesses of stimuli that result in the (de)formation of our senses, including during our free time. In this article, we questioned the production of the sight and its role in the tourism context.
Verônica Werle, Alexandre Fernandez Vaz
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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