Results 71 to 80 of about 55,083,857 (233)
Seeing conspiracy theorists everywhere as a conspiracy paradox
Communications PsychologyConcerns about the consequences of conspiracy theories have grown. Widespread belief in unfounded conspiracy theories is only one associated risk. Conversely, academics mustn’t commit the reverse error, in adopting a Protective Conspiracy Framing and ...
Nicolas Vermeulen
doaj +1 more source
Eugesta, 2018 Identifying an allusion to classical Greco-Roman poetry in a monologue (or prosopopoeia) of a cowherd by the fourth century Latin poet, Paulinus of Nola (c. 18.276-80), this article explains the emergence of the category of labor as a response to a
Alex Dressler
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Seeing in: Two-fold, three-fold? [PDF]
, 2016 Taking Richard Wollheim’s theory that seeing pictures is a two-fold experience of perception, (between the marked surface of the physical object and something depicted in its surface), this paper analyses my recent practice of creating artworks that ...
Robinson, C.
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Education of Senses in Free Time: seeing as entertainment
Educação & Realidade, 2020 Nowadays we are increasingly subordinated by the excesses of stimuli that result in the (de)formation of our senses, including during our free time. In this article, we questioned the production of the sight and its role in the tourism context.
Verônica Werle, Alexandre Fernandez Vaz
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source