Results 31 to 40 of about 232,315 (296)

Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study [PDF]

, 2013
Objectives: To assess long-term golimumab efficacy/safety in patients with active psoriatic arthritis (PsA).<p></p> Methods Adult PsA patients (≥3 swollen, ≥3 tender joints, active psoriasis) were randomly assigned to ...
Beutler, A., Gladman, D.D., Kavanaugh, A., Krueger, G.G., Mack, M., McInnes, I.B., Mease, P.J., Mudivarthy, S., van der Heijde, D., Xu, W., Xu, Z.   +10 more
core   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster   +13 more
wiley   +1 more source

Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping

Nature Communications
Proteogenomics studies generate hypotheses on protein function and provide genetic evidence for drug target prioritization. Most previous work has been conducted using affinity-based proteomics approaches.
Karsten Suhre, Guhan Ram Venkataraman, Harendra Guturu, Anna Halama, Nisha Stephan, Gaurav Thareja, Hina Sarwath, Khatereh Motamedchaboki, Margaret K. R. Donovan, Asim Siddiqui, Serafim Batzoglou, Frank Schmidt   +11 more
doaj   +1 more source

Construction and Validation of New Nomograms to Predict Risk and Prognostic Factors of Breast Cancer Bone Metastasis in Asian Females: A Population-Based Retrospective Study

International Journal of General Medicine, 2021
Junsen Deng,1,* Di Zhang,2,* Wenming Zhang,1 Junhui Li2 1Department of Orthopedics Surgery, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Zhengzhou, 45000, Henan, People’s Republic of China; 2Department of ...
Deng J, Zhang D, Zhang W, Li J
doaj  

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Longitudinal deep multi-omics profiling in a CLN3 Δex7/8 minipig model identifies biomarker signatures of disease

Communications Medicine
Background Development of therapies for CLN3 disease, a rare pediatric lysosomal storage disorder, has been hindered by the lack of etiological insights and translatable biomarkers to clinics. Methods We used a deep multi-omics approach to discover blood-
Mitchell J. Rechtzigel, Brittany Lee, Christine Neville, Ting Huang, Ramón Díaz, Alex Rosa Campos, Khatereh Motamedchaboki, Daniel Hornburg, Tyler B. Johnson, Vicki J. Swier, Jill M. Weimer, Jon J. Brudvig   +11 more
doaj   +1 more source

Survival Analysis of Hepatosplenic T Cell Lymphoma: A Population-Based Study Using SEER

International Journal of General Medicine, 2021
Yajun Li,1 Kailin Chen,2 Chaohui Zuo,3 Ruolan Zeng,1 Yizi He,1 Xiaoyan Chen,4 Ling Xiao,5 Hui Zhou1 1Department of Lymphoma and Hematology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University ...
Li Y, Chen K, Zuo C, Zeng R, He Y, Chen X, Xiao L, Zhou H   +7 more
doaj  

Survival nomogram for different grades of gastric cancer patients based on SEER database and external validation cohort

Frontiers in Oncology, 2022
BackgroundInfluencing factors varied among gastric cancer (GC) for different differentiation grades which affect the prognosis accordingly. This study aimed to develop a nomogram to effectively identify the overall survival (OS).MethodsTotally, 9,568 ...
Lei Hu, Lei Hu, Kang Yang, Kang Yang, Yue Chen, Chenyu Sun, Xu Wang, Shaopu Zhu, Shiyi Yang, Guodong Cao, Maoming Xiong, Bo Chen, Bo Chen   +12 more
doaj   +1 more source

Modeling county level breast cancer survival data using a covariate-adjusted frailty proportional hazards model

, 2015
Understanding the factors that explain differences in survival times is an important issue for establishing policies to improve national health systems.
Hanson, Timothy, Jara, Alejandro, Zhang, Jiajia, Zhou, Haiming   +3 more
core   +1 more source

Effects of Cancer Treatment on Somatosensory and Nociceptive Processing in Children and Adolescents: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger, Laura Walz, Michael C. Frühwald, Stefan Lautenbacher, Miriam Kunz   +4 more
wiley   +1 more source