Results 81 to 90 of about 36,688 (264)

Development and validation of a nomogram for prognosis of bone metastatic disease in patients with esophageal squamous cell carcinoma: A retrospective study in the SEER database and China cohort

Journal of Bone Oncology
Purpose: Esophageal squamous cell carcinoma (ESCC) is a prevalent malignant tumor worldwide, and individuals with ESCC and bone metastasis (BM) often face a challenging prognosis.
Bo Huang, Wei-Dong Wang, Fang-Cai Wu, Xiao-Mei Wang, Bu-Qing Shao, Ying-Miao Lin, Guo-Xing Zheng, Gui-Qiang Li, Can-Tong Liu, Yi-Wei Xu, Xin-Jia Wang   +10 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Establishment of Risk-Prediction Model for Axillary Lymph-Node Metastasis in Microinvasive Breast Cancer Based on SEER Database

Zhongliu Fangzhi Yanjiu
ObjectiveTo analyze the factors influencing axillary lymph-node metastasis (ALNM) in microinvasive breast cancer (MIBC) patients, as well as to establish the risk-prediction model of ipsilateral ALNM in MIBC patients.
Chenghao LIU, Ting LU, Fang QIAN, Yuanbing XU, Chaohua HU, Haoyuan SHEN   +5 more
doaj   +1 more source

Predictors of Cytoreductive Nephrectomy for Metastatic Kidney Cancer in SEER and Metropolitan Detroit Databases

Journal of Kidney Cancer and VHL, 2019
Patients without cytoreductive nephrectomy (CN) are inadequately represented in metastatic RCC clinical trials. The characteristics that impact the decision of CN were explored in the SEER database.
Ulka Vaishampayan, MD, Julie George, Fawn Vigneau   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Demographic, clinical and pathologic characteristics of patients with large cell neuroendocrine carcinoma (LCNEC) of the lung from the SEER 18 database, 2004–2015 (n = 3048). [PDF]

, 2019
Demographic, clinical and pathologic characteristics of patients with large cell neuroendocrine carcinoma (LCNEC) of the lung from the SEER 18 database, 2004–2015 (n = 3048).
Yanqi He (3714628), Yu Chen (29959), Han Liu (288039), Shuai Wang (109515)   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Concordance of Gleason score on biopsy and after prostatectomy: A SEER database analysis. [PDF]

, 2015
50 Background: The Gleason score (GS) is a well-established prognostic factor and is used to guide clinical decision-making for patients with prostate cancer.
Manuj Agarwal, Elliot B. Navo, David Schreiber, David Schwartz, Andrew Thomas Wong   +4 more
core   +1 more source