Results 91 to 100 of about 381,423 (286)

Perception of Fa by non-native listeners in a study abroad context [PDF]

open access: yes, 2012
The present study aims at exploring the under-investigated interface between SA and L2 phonological development by assessing the impact of a 3-month SA programme on the pronunciation of a group of 23 Catalan/Spanish learners of English (NNSs) by means of
Avello Pilar   +2 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Role of Virtual Monoenergetic Images in the Assessment of Vessel Enhancement in Segmental Level in Third-Generation Dual-Source Dual-Energy CT Pulmonary Angiography—A Prospective Study

open access: yesIndian Journal of Radiology and Imaging
Introduction Pulmonary embolism is the third most common cause of cardiovascular death worldwide and imaging plays a pivotal role in establishing the diagnosis.
Vijayakumaran Ethiraju   +7 more
doaj   +1 more source

Revisiting the Status of Speech Rhythm [PDF]

open access: yes, 2002
Text-to-Speech synthesis offers an interesting manner of synthesising various knowledge components related to speech production. To a certain extent, it provides a new way of testing the coherence of our understanding of speech production in a highly ...
Zellner Keller, Dr. Brigitte
core   +1 more source

Finite-Element Analysis of Shear-off Failure of Keyed Dry Joints in Precast Concrete Segmental Bridges [PDF]

open access: yes, 2014
This article has been made available through the Brunel Open Access Publishing Fund.The structural behaviour of precast concrete segmental bridges is largely dependent on the behaviour of the joints between segments.
Giulio Alfano   +5 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The behaviour of a two-component backfilling grout used in a Tunnel-Boring Machine [PDF]

open access: yes, 2011
The instantaneous filling of the annulus that is created behind the segment lining at the end of the tail during the TBM advance is an operation of paramount importance.
Borio, Luca   +2 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

A decision-theoretic approach for segmental classification

open access: yes, 2013
This paper is concerned with statistical methods for the segmental classification of linear sequence data where the task is to segment and classify the data according to an underlying hidden discrete state sequence.
Holmes, Christopher C., Yau, Christopher
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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