Results 51 to 60 of about 268,926 (258)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Segmental testicular infarction following cysto-prostatectomy

open access: yesUrology Annals, 2011
Segmental (partial) testicular infarction is a very rare condition of unknown cause in more than 70% of cases. Several predisposing conditions have been described, but to our knowledge, this is the first documented case and often overlooked complication ...
Adam I Alleemudder   +2 more
doaj   +1 more source

Superimposed segmental manifestation of cherry angiomas.

open access: yes, 2011
Cherry angioma is a common, acquired, vascular proliferation, probably of a polygenic mode of inheritance. Segmental manifestation of multiple cherry angiomas associated with the development of non-segmental lesions has not yet been reported. We describe
Jaeger, T;Andres, C;Hein, R;Ring, J;Chen, W
core   +1 more source

Alt ekstremitenin segmental zoster parezisi: Olgu sunumu Segmental zoster paresis of the lower extremity: Case report

open access: yes, 2023
Herpes zoster (HZ) is a segmental vesicular eruption, pain, and sensorial symptoms. Segmental motor weakness can rarely be seen as a complication of HZ. Here, we present two cases of motor paresis associated with HZ, case 1 was L2 and L3 segmental motor ...
Balta, Selin, Köknel Talu, Gül
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Pengaruh Panjang Sambungan Pada Beton Prategang Segmental Bertulangan Limbah Ban

open access: yesJurnal Teknik Sipil dan Perencanaan, 2017
Prestressed concrete with reinforcement of waste tires can improve significantly the flexural strength. The problems when applied in the project is difficult to move from the production site to the location of the structure.
Agus Maryoto
doaj  

Congenital agminated segmental nevi of the chest [PDF]

open access: yes, 2013
Grouped patterns of pigmented lesions are infrequent. Of the several reports of agminated nevi, most have been Spitz nevi or blue nevi. The distribution of these nevi is often segmental, following a dermatome or the lines of Blaschko. Most segmental nevi
Ezra, Navid   +4 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Study on mechanical properties of large deformation segmental cement-based honeycomb structure

open access: yesFrontiers in Materials
Honeycomb structures provide a new means of controlling and supporting the tunnel envelope. However, traditional honeycomb structures have low strength and poor stability, and are prone to stress concentration and instability, further limiting their ...
Gang Song   +7 more
doaj   +1 more source

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