Results 51 to 60 of about 4,422 (176)

Resolving CYP2D6 Structural Complexity with Long‐Read Sequencing: Implications for Tamoxifen Precision Dosing in Thai Breast Cancer Patients

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 774-785, September 2026.
Cytochrome P450 2D6 (CYP2D6)‐mediated bioactivation of tamoxifen to endoxifen is a key determinant of therapeutic efficacy in estrogen receptor‐positive breast cancer. In Asian populations, the high prevalence of structurally complex CYP2D6 alleles complicates conventional genotyping, limiting accurate genotype–phenotype correlation.
Usa Boonyuen, Sirinyatorn Talukam, Beatriz Aira C. Jacob, Wayu Matphong, Kamonwan Chamchoy, Onrapak Reamtong, Nuntana Meesiripan, Junya Yamagishi, Matthew Phanchana, Chayanoot Rattadilok   +9 more
wiley   +1 more source

A 40‐year‐old woman with a spinal mass

Brain Pathology, EarlyView.
Melissa Mejia‐Bautista, Margarita Loxas, Pouya Jamshidi, Drew Duckett, Jean‐Paul Wolinsky, Jared T. Ahrendsen   +5 more
wiley   +1 more source

Sexual Silence in Breast Cancer Survivorship: A Secondary Qualitative Study of Healthcare Practices and Sexual Concerns

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims In routine breast cancer follow‐up care, sexual concerns are rarely discussed, shaping how women understand and respond to post‐treatment changes. This study examined how survivorship care practices influence the expression and recognition of sexual concerns among women after breast cancer treatment.
Mina Esmkhani, Charrlotte Seib, Armin Ariana   +2 more
wiley   +1 more source

Foot drop in generalized herpes zoster: L5‑predominant polyradiculitis as a rare complication – a case report

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Anna Malfertheiner, Alexander Mensch, Burkhard Kreft   +2 more
wiley   +1 more source

Clinical Rationale of Dual‐Parameter Tumor Markers Reporting Without Reliance on Normal Reference Ranges

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
We recommend the current practice of tumor marker reporting to upgrade to two‐figure format to include a specific growth rate in parentheses. This can be of great clinical importance, especially in the subnormal range. ABSTRACT Introduction This review offers clinicians a novel view of tumor markers (TM).
Jurate Civinskaite, Daiva Gudaviciene, Gintaras Zaleskis, Aleksandras Petrauskas, Dainius Characiejus, Tatjana Ivaskiene   +5 more
wiley   +1 more source

Depression and conservative surgery for breast cancer

Clinics, 2010
BACKGROUND: Depression is prevalent among women and associated with reduced quality of life, and therefore it is important to determine its incidence in adult women, especially in those with breast cancer.
Mauriceia C. L. de Medeiros, Daniela F. Veiga, Miguel Sabino Neto, Luis E F. Abla, Yara Juliano, Lydia M. Ferreira   +5 more
doaj   +1 more source

Evaluation of the Feasibility, Safety, and Effectiveness of a Tailored Enhanced Recovery After Surgery Protocol for Gastroepiploic Vascularized Lymph Node Transfer in Breast Cancer‐Related Upper Extremity Lymphedema: A Preliminary Retrospective Comparative Study

Microsurgery, Volume 46, Issue 6, September 2026.
ABSTRACT Background Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative pathways designed to reduce surgical stress, accelerate recovery, and improve resource utilization. Although ERAS principles have been increasingly adopted in microsurgery, their application in vascularized lymph node transfer (VLNT), particularly using ...
Federico Lo Torto, Bilel Dribine, Alessia Pagnotta, Andrea Loreti, Giuseppe Cavallaro   +4 more
wiley   +1 more source

Brazilian Portuguese validation of the breast cancer-related modules of the BREAST-Q

Frontiers in Oncology
BackgroundThe rising incidence of breast cancer and the growing number of survivors underscore the need for further research into quality of life.
Antônio Bailão Junior, Antônio Bailão Junior, Idam de Oliveira-Junior, Idam de Oliveira-Junior, Guilherme Novita Garcia, João Bosco Ramos Borges, Vivian Aparecida Brancaglioni, Carlos Eduardo Paiva, René Aloisio da Costa Vieira, René Aloisio da Costa Vieira, René Aloisio da Costa Vieira   +10 more
doaj   +1 more source

Relationship between bisphosphonate use and risks of recurrence and mortality among hormone receptor–positive and triple‐negative breast cancer patients

Cancer, Volume 132, Issue 16, 15 August 2026.
Abstract Background Bisphosphonates (BPs) are routinely used as an adjuvant therapy for breast cancer to reduce the risk of bone recurrences given their anti‐resorptive effects on bones and antitumor characteristics. However, there remains limited evidence regarding their utility across different subtypes. Methods In this population‐based cohort study,
Liuye Huang, Linda S. Cook, Mei‐Tzu C. Tang, David R. Doody, Ulrike Peters, Wei Sun, Jeroen R. Huyghe, Kathleen E. Malone, Christopher I. Li   +8 more
wiley   +1 more source