Automatic measurement of proximal femoral morphological parameters using point cloud semantic segmentation technology. [PDF]
Sci RepWang Y, Yang Q, Li J, Wang K, Tang M.
europepmc +1 more source
Novel Phenotypes and Deep Intronic Variant Expand TH‐Associated Dopa‐Responsive Dystonia Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Approximately 20% of dopa‐responsive dystonia (DRD) cases remain genetically unresolved. Using whole‐genome sequencing, we identified two TH variants in a young DRD patient, including a novel deep intronic variant. Minigene assays confirmed that this variant causes aberrant splicing.
Xiaosheng Zheng +6 more
wiley +1 more source
Robust semi-automatic vessel tracing in the human retinal image by an instance segmentation neural network. [PDF]
Sci AdvChen S, Hoang L, Kashani AH, Yi J.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Certain frontotemporal lobar degeneration subtypes, including TDP‐A and B, can either occur sporadically or in association with specific genetic mutations. It is uncertain whether syndromic or imaging features previously associated with these patient groups are subtype or genotype specific.
Sean Coulborn +17 more
wiley +1 more source
Longitudinal Trajectories of Digital Cognitive Biomarkers for Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is one of the most common and debilitating symptoms of relapsing–remitting multiple sclerosis (RRMS). Digital cognitive biomarkers require less time and resources and are rapidly gaining popularity in clinical settings.
Yi Chao Foong +17 more
wiley +1 more source
Plant stem and leaf segmentation and phenotypic parameter extraction using neural radiance fields and lightweight point cloud segmentation networks. [PDF]
Front Plant SciQiao G, Zhang Z, Niu B, Han S, Yang E.
europepmc +1 more source
Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi +7 more
wiley +1 more source
Dual-Filter Cross Attention and Onion Pooling Network for Enhanced Few-Shot Medical Image Segmentation. [PDF]
Sensors (Basel)Ni L, Liu Y, Zhang Z, Li Y, Zhang J.
europepmc +1 more source
Claustrum Volume Is Reduced in Multiple Sclerosis and Predicts Disability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The claustrum is a small, thin structure of predominantly gray matter with broad connectivity and enigmatic function. Little is known regarding the impact of claustrum pathology in multiple sclerosis (MS). Methods This study assessed whether claustrum volume was reduced in MS and whether reductions were associated with specific ...
Nicole Shelley +5 more
wiley +1 more source