Results 111 to 120 of about 39,077 (276)

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia

Advanced Healthcare Materials, EarlyView.
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi, Tanveer Ul Islam, Oscar M.J.A. Stassen, Naomie Amsing, Jan de Boer, Jaap M.J. den Toonder   +5 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

An optical technology study on large aperture telescopes [PDF]

The difficult and crucial problem of selecting a suitable telescope concept for an advanced space observatory was examined. To this end two and four mirror telescopes were analyzed and compared.
Korsch, D.
core   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

The Cherenkov Telescope Array Large Size Telescope

, 2013
The two arrays of the Very High Energy gamma-ray observatory Cherenkov Telescope Array (CTA) will include four Large Size Telescopes (LSTs) each with a 23 m diameter dish and 28 m focal distance.
Ambrosi, G., Awane, Y., Baba, H., Bamba, A., Barceló, M., Barrio, J. A., Bigas, O. Blanch, Boix, J., Brunetti, L., Carmona, E., Chabanne, E., Chikawa, M., Colin, P., Conteras, J. L., Cortina, J., Dazzi, F., de Almeida, U. Barres, Deangelis, A., Deleglise, G., Delgado, C., Dubois, F., Díaz, C., Fiasson, A., Fink, D., Flour, T. Le, Fouque, N., Freixas, L., Fruck, C., Gadola, A., García, R., Gascon, D., Geffroy, N., Giglietto, N., Giordano, F., Grañena, F., Gunji, S., Hagiwara, R., Hamer, N., Hanabata, Y., Hassan, T., Hatanaka, K., Haubold, T., Hayashida, M., Hermel, R., Herranz, D., Hirotani, K., Inoue, S., Inoue, Y., Ioka, K., Jablonski, C., Kagaya, M., Katagiri, H., Kishimoto, T., Kodani, K., Kohri, K., Konno, Y., Koyama, S., Kubo, H., Kushida, J., Lamanna, G., Lorenz, E., López, R., López-Moya, M., Majumdar, P., Manalaysay, A., Mariotti, M., Martínez, G., Martínez, M., Mazin, D., Miranda, J. M., Mirzoyan, R., Monteiro, I., Moralejo, A., Murase, K., Nagataki, S., Nakajima, D., Nakamori, T., Nishijima, K., Noda, K., Nozato, A., Ohira, Y., Ohishi, M., Ohoka, H., Okumura, A., Orito, R., Panazol, J. L., Paneque, D., Paoletti, R., Paredes, J. M., Pauletta, G., Podkladkin, S., Prast, J., Rando, R., Reimann, O., Ribó, M., Rosier-Lees, S., Saito, K., Saito, T., Saito, Y., Sakaki, N., Sakonaka, R., Sanuy, A., Sasaki, H., Sawada, M., Scalzotto, V., Schultz, S., Schweizer, T., Shibata, T., Shu, S., Sieiro, J., Stamatescu, V., Steiner, S., Straumann, U., Sugawara, R., Tajima, H., Takami, H., Tanaka, M., Tanaka, S., Tejedor, L. A., Terada, Y., Teshima, M., Totani, T., Ueno, H., Umehara, K., Vollhardt, A., Wagner, R., Wetteskind, H., Yamamoto, T., Yamazaki, R., Yoshida, A., Yoshida, T., Yoshikoshi, T.   +131 more
core   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

Advanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti, Valerio Di Lisio, Lucia Cardo, Alessandro Camilli, Estela Moretón Alfonsín, Daniele Cangialosi, Amaia Iturrospe Ibarra, Arantxa Arbe, Maurizio Prato   +8 more
wiley   +1 more source