Results 41 to 50 of about 211,200 (266)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Segmented Iba1-Positive Processes of Microglia in Autism Model Marmosets

open access: yesFrontiers in Cellular Neuroscience, 2019
Autism spectrum disorder (ASD) is one of the most widespread neurodevelopmental disorders, characterized by impairment in social interactions, and restricted stereotyped behaviors.
Tomomi Sanagi   +6 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

DeepLabV3-Refiner-Based Semantic Segmentation Model for Dense 3D Point Clouds

open access: yesRemote Sensing, 2021
Three-dimensional virtual environments can be configured as test environments of autonomous things, and remote sensing by 3D point clouds collected by light detection and range (LiDAR) can be used to detect virtual human objects by segmenting collected ...
Jeonghoon Kwak, Yunsick Sung
doaj   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

Machine Learning for Chinese Corporate Fraud Prediction: Segmented Models Based on Optimal Training Windows

open access: yesInformation
We propose a comprehensive and practical framework for Chinese corporate fraud prediction which incorporates classifiers, class imbalance, population drift, segmented models, and model evaluation using machine learning algorithms.
Chang Chuan Goh   +3 more
doaj   +1 more source

Numerical Investigation on Hybrid Rocket Motors with Star-Segmented Rotation Grain

open access: yesAerospace, 2022
A novel fuel grain configuration comprising two star-segmented grains is proposed. The effect of the rotation, mid-chamber length, and segmented position on the fuel regression rate and the combustion efficiency in hybrid rocket motors with star ...
Hui Tian   +5 more
doaj   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel   +15 more
wiley   +1 more source

Viral genome segmentation can result from a trade-off between genetic content and particle stability. [PDF]

open access: yesPLoS Genetics, 2011
The evolutionary benefit of viral genome segmentation is a classical, yet unsolved question in evolutionary biology and RNA genetics. Theoretical studies anticipated that replication of shorter RNA segments could provide a replicative advantage over ...
Samuel Ojosnegros   +7 more
doaj   +1 more source

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