Results 81 to 90 of about 82,789 (258)

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Speech segmentation using regression fusion of boundary predictions

Computer Speech & Language, 2010
In the present work we study the appropriateness of a number of linear and non-linear regression methods employed on the task of combining multiple phonetic boundary predictions. The proposed fusion schemes are independent of the implementation of the individual segmentation engines as well as from their number.
Mporas, Iosif, Ganchev, Todor, Fakotakis, Nikos   +2 more
openaire   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Short-term forecasting models for automated data backup system: segmented regression analysis

Acta Scientiarum: Technology, 2020
The Information and Communication Technology (ICT) becomes a critical area to business success; organizations need to adopt additional measures to ensure the availability of their services.
Leandro Duarte Pereira, Pedro Paulo Balestrassi, Vinicius de Carvalho Paes, Anderson Paulo de Paiva, Rogério Santana Peruchi, Ronã Rinston Amauri Mendes   +5 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Implicações da aplicação de fungicida na adaptabilidade e estabilidade de rendimento de grãos em aveia branca Implications of fungicide application to adaptability and stability of grain yield in oat

Ciência Rural, 2004
Vinte genótipos de aveia (Avena sativa L.), testados em 13 ambientes, foram submetidos à análise de adaptabilidade e estabilidade com o objetivo de avaliar o efeito da utilização de fungicida nestes parâmetros, através do modelo de regressão segmentado ...
Claudir Lorencetti, Fernando Irajá Félix de Carvalho, Volmir Sergio Marchioro, Giovani Benin, Antônio Costa de Oliveira, Elmar Luiz Foss   +5 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Handling Missing Values in Interrupted Time Series Analysis of Longitudinal Individual-Level Data

Clinical Epidemiology, 2020
Juan Carlos Bazo-Alvarez,1,2 Tim P Morris,3 Tra My Pham,3 James R Carpenter,3,4 Irene Petersen1,5 1Research Department of Primary Care and Population Health, University College London (UCL), London, UK; 2Instituto de Investigación, Universidad Cat&
Bazo-Alvarez JC, Morris TP, Pham TM, Carpenter JR, Petersen I   +4 more
doaj  

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source