Results 1 to 10 of about 10,602,103 (140)

Differential Expression of Immune Checkpoints TIM-3, LAG-3, TIGIT, and Siglec-7 on Circulating Natural Killer Cells - Insights from Healthy Donors Compared to Gastric Cancer Patients. [PDF]

Oncol Res Treat
Introduction: The complex, multifactorial nature of gastric cancer presents significant challenges in the development of effective immunotherapies. Targeting immune checkpoints has emerged as a promising strategy, with blockade therapies demonstrating ...
Seiffert S, Seiffert S, Blaudszun AR, Shibru B, Körfer J, Köhl U, Fricke S, Sack U, Boldt A.   +8 more
europepmc   +2 more sources

Non-invasive assessment of cultivar and sex of Cannabis sativa L. by means of hyperspectral measurement. [PDF]

Plant Environ Interact, 2023
Cannabis sativa L. is a versatile crop attracting increasing attention for food, fiber, and medical uses. As a dioecious species, males and females are visually indistinguishable during early growth. For seed or cannabinoid production, a higher number of
Matros A, Menz P, Gill AR, Santoscoy A, Dawson T, Seiffert U, Burton RA.   +6 more
europepmc   +2 more sources

Proteomic Correlates and Prognostic Significance of Kidney Injury in Heart Failure With Preserved Ejection Fraction. [PDF]

J Am Heart Assoc
Background Kidney disease is common in heart failure with preserved ejection fraction (HFpEF). However, the biologic correlates and prognostic significance of kidney injury (KI), in HFpEF, beyond the estimated glomerular filtration rate (eGFR), are ...
Salman O, Zhao L, Cohen JB, Dib MJ, Azzo JD, Gan S, Richards AM, Pourmussa B, Doughty R, Javaheri A, Mann DL, Rietzschel E, Zhao M, Wang Z, Ebert C, van Empel V, Kammerhoff K, Maranville J, Gogain J, Dennis J, Schafer PH, Seiffert D, Gordon DA, Ramirez-Valle F, Cappola TP, Chirinos JA.   +25 more
europepmc   +2 more sources

Several Double Inequalities for Integer Powers of the Sinc and Sinhc Functions with Applications to the Neuman–Sándor Mean and the First Seiffert Mean

Axioms, 2022
In the paper, the authors establish a general inequality for the hyperbolic functions, extend the newly-established inequality to trigonometric functions, obtain some new inequalities involving the inverse sine and inverse hyperbolic sine functions, and apply these inequalities to the Neuman–Sándor mean and the first Seiffert mean.
Wen-Hui Li, Qi-Xia Shen, Bai-Ni Guo
openaire   +2 more sources

ANK2 loss-of-function variants are associated with epilepsy, and lead to impaired axon initial segment plasticity and hyperactive network activity in hiPSC-derived neuronal networks

Human Molecular Genetics, 2023
Purpose To characterize a novel neurodevelopmental syndrome due to loss-of-function (LoF) variants in Ankyrin 2 (ANK2), and to explore the effects on neuronal network dynamics and homeostatic plasticity in human-induced pluripotent stem cell-derived ...
Maria W A Teunissen, E. Lewerissa, Eline J. H. van Hugte, Shan Wang, C. Ockeloen, D. Koolen, R. Pfundt, C. Marcelis, E. Brilstra, J. Howe, S. Scherer, X. Le Guillou, F. Bilan, M. Primiano, J. Roohi, A. Piton, A. de Saint Martin, S. Baer, Simone Seiffert, K. Platzer, R. Jamra, S. Syrbe, J. Doering, Shenela Lakhani, S. Nangia, C. Gilissen, R. Vermeulen, R. Rouhl, H. Brunner, M. Willemsen, N. N. Kasri   +30 more
semanticscholar   +1 more source

Simultaneous Inhibition of PI3Kgamma and PI3Kdelta Deteriorates T-cell Function With Implications for Chronic Lymphocytic Leukemia

HemaSphere, 2023
Chronic lymphocytic leukemia (CLL) is a common and incurable B-cell malignancy. Recent therapeutic approaches that target the B-cell receptor signaling pathway include inhibition of phosphatidylinositol-3-kinase (PI3K).
Sebastian Faehling, M. Coelho, A. Floerchinger, C. Schneider, S. Stilgenbauer, P. Lichter, M. Seiffert, P. Roessner   +7 more
semanticscholar   +1 more source

Tracing attosecond electron emission from a nanometric metal tip [PDF]

Nature, 2023
Solids exposed to intense electric fields release electrons through tunnelling. This fundamental quantum process lies at the heart of various applications, ranging from high brightness electron sources in d.c.
P. Dienstbier, L. Seiffert, T. Paschen, A. Liehl, A. Leitenstorfer, T. Fennel, P. Hommelhoff   +6 more
semanticscholar   +1 more source

Combining ibrutinib and checkpoint blockade improves CD8+ T-cell function and control of chronic lymphocytic leukemia in E-TCL1 mice

Haematologica, 2020
Ibrutinib is a Bruton’s tyrosine kinase (BTK) inhibitor approved for the treatment of multiple B-cell malignancies, including chronic lymphocytic leukemia (CLL).
Bola S Hanna, H. Yazdanparast, Y. Demerdash, P. Roessner, R. Schulz, P. Lichter, S. Stilgenbauer, M. Seiffert   +7 more
semanticscholar   +1 more source

Some sharp inequalities involving Seiffert and other means and their concise proofs [PDF]

, 2012
In the paper, by establishing the monotonicity of some functions involving the sine and cosine functions, the authors provide concise proofs of some known inequalities and find some new sharp inequalities involving the Seiffert, contra-harmonic ...
Jiang, Wei-Dong, Qi, Feng
core   +1 more source

On Seiffert-like means [PDF]

, 2013
We investigate the representation of homogeneous, symmetric means in the form M(x,y)=\frac{x-y}{2f((x-y)/(x+y))}. This allows for a new approach to comparing means. As an example, we provide optimal estimate of the form (1-\mu)min(x,y)+ \mu max(x,y)
Witkowski, Alfred
core   +2 more sources