ABSTRACT Objective Evaluate the effects of osilodrostat short‐ and long‐term treatment on health‐related quality of life (HRQoL) in Cushing's disease. Design LINC 3 and LINC 4 studies (pooled analysis). Patients 185 patients (mean baseline total scores: Cushing's Quality of Life [CushingQoL], 44.0; Beck Depression Inventory II [BDI‐II], 15.6; EuroQol ...
John Newell‐Price +6 more
wiley +1 more source
A large-scale seismic risk assessment framework using enhanced FEMA P-58 and Bayesian network inference: a case study of District 2, Tehran. [PDF]
Hajirostami R, Banazadeh M.
europepmc +1 more source
The Rising Tide Lifts Some Interest Rates: Climate Change, Natural Disasters, and Loan Pricing
ABSTRACT Banks adjust loan spreads after observing natural disasters linked to climate change. We isolate this updating process by identifying loans to borrowers at risk of, but not directly affected by, such disasters. Loan spreads for these borrowers spike in both primary and secondary markets, while no such updating occurs for non–climate‐related ...
RICARDO CORREA +3 more
wiley +1 more source
Failure mechanisms and recycling potential of railway sleepers damaged during the 2023 Kahramanmaraş earthquakes. [PDF]
Maras MM, Tas H, Yigit HG.
europepmc +1 more source
Dam Management in the Era of Climate Change
ABSTRACT Climate change has a dramatic impact, particularly by concentrating rainfall into a few short periods, interspersed with long dry spells. In this context, the role of dams is crucial. We consider the optimal control of a dam, where the water level must neither exceed a designated safety threshold nor fall below a minimum level to ensure ...
Cristina Di Girolami +3 more
wiley +1 more source
Mechanism of stress relief by deep-hole blasting in floor drainage roadways and its effectiveness evaluation. [PDF]
Yan CL, Dou LM, Mu ZL, Lu FZ, Jian LL.
europepmc +1 more source
Quantifying the Role of 3D Fault Geometry Complexities on Slow and Fast Earthquakes
Abstract Traditional models of slow slip events (SSEs) oversimplify fault geometry, although imaging shows subduction faults are segmented and complex. We examine how fault interactions control slip behavior using 3D quasi‐dynamic simulations of two parallel faults with uniform rate‐weakening friction accelerated by hierarchical matrices.
J. Cheng +4 more
wiley +1 more source
Effects of ground motion spectral characteristics on RC frame fragility considering liquefaction. [PDF]
Fei Y, Chen LW, Gan SC, Tang LZ, Cui Z.
europepmc +1 more source
Abstract Slow slip events (SSEs) in the Cascadia subduction zone exhibit along‐strike segmentation, where the central segment has longer recurrence intervals but smaller moments. We quantify the controls on this variability by combining geodetic inter‐SSE coupling inversion with Bayesian inference of a quasi‐dynamic rate‐and‐state friction SSE‐cycle ...
Yohai Magen +2 more
wiley +1 more source
Performance evaluation of steel frames with a novel replaceable pipe damper system. [PDF]
Taiyari F, Roshani J.
europepmc +1 more source

