Effect of Ellagic Acid on Seizure Threshold in Two Acute Seizure Tests in Mice [PDF]
Molecules, 2021 Ellagic acid (EA) is a natural dietary polyphenol that has many beneficial properties, including anti-inflammatory, antioxidant, antiviral, antibacterial, and neuroprotective effects.
Mateusz Pieróg +4 more
doaj +3 more sources
Salvinorin A Does Not Affect Seizure Threshold in Mice [PDF]
Molecules, 2020 The κ-opioid receptor has recently gained attention as a new molecular target in the treatment of many psychiatric and neurological disorders including epilepsy.
Katarzyna Socała +2 more
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Drugs that lower the seizure threshold [PDF]
Adverse Drug Reaction Bulletin, 2016 SummaryDrugs with potential to lower the seizure threshold are numerous and diverse. Whether they contribute to clinically overt seizures depends on the dosage in which they are taken, the time-course of their effects and the susceptibility of the patient. Crucially, however, their contribution to seizure risk is potentially modifiable.
A. W. Hitchings
semanticscholar +5 more sources
4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold. [PDF]
Proc Natl Acad Sci U S A, 2021 Significance In numerous models of neurodevelopmental disorders and epilepsy, genetic mutations associated with enhanced mTORC1 activity engender an increase in the susceptibility to epileptic seizures.
Sharma V +17 more
europepmc +2 more sources
Oxygenated Water Increases Seizure Threshold in Various Rodent Seizure Models. [PDF]
Int J Mol Sci, 2022 Oxygenated water (OW) contains more oxygen than normal drinking water. It may induce oxygen enrichment in the blood and reduce oxidative stress. Hypoxia and oxidative stress could be involved in epilepsy. We aimed to examine the effects of OW-treated vs.
Kwon HH +6 more
europepmc +3 more sources
Deep Brain Stimulation Increases Seizure Threshold by Altering REM Sleep and Delta Powers During NREM Sleep. [PDF]
Front Neurol, 2020 We previously demonstrated that seizure occurrences at different zeitgeber times alter sleep and circadian rhythm differently. On the other hand, the synchronized delta wave of electroencephalogram (EEG) during non-rapid eye movement (NREM) sleep ...
Tseng HT, Hsiao YT, Yi PL, Chang FC.
europepmc +2 more sources
Scorpion Envenomation of Lactating Rats Decreases the Seizure Threshold in Offspring [PDF]
Toxins, 2021 Few data are available in the literature describing the long-term effects of envenoming in the perinatal period. In this study, the relationship between envenoming of lactating rats and possible behavioral changes in the mother and in her offspring were ...
Marina de Oliveira Rodrigues Barbosa +2 more
doaj +2 more sources
Can Propofol Lead to an Increase in Seizure Threshold Over the Course of Electroconvulsive Therapy? [PDF]
Clin Psychopharmacol Neurosci, 2019 Objective To evaluate the effects of 2 different dose regimens of propofol (low dose: < 1 mg/kg, high dose: ≥ 1 mg/kg) on the duration of the seizures, the required energy for the seizures, and the seizure threshold over the course of electroconvulsive ...
Aytuluk HG +4 more
europepmc +2 more sources
Optogenetic and chemogenetic manipulation of seizure threshold in mice [PDF]
STAR Protocols, 2023 Summary: Here, we present a protocol using optogenetics or chemogenetics to assess the neuronal circuits contributing to seizure initiation. Both approaches allow for targeted control of neuronal populations in vivo and can be combined with experimental ...
Julia A. Kravchenko +2 more
doaj +2 more sources
Assessment of the Anticonvulsant Potency of Ursolic Acid in Seizure Threshold Tests in Mice. [PDF]
Neurochem Res, 2018 Ursolic acid (UA) is a plant derived compound which is also a component of the standard human diet. It possesses a wide range of pharmacological properties, i.e., antioxidant, anti-inflammatory, antimicrobial and antitumor, which have been used in folk ...
Nieoczym D, Socała K, Wlaź P.
europepmc +2 more sources