Results 271 to 280 of about 1,591,675 (322)
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Etidocaine, Bupivacaine, and Lidocaine Seizure Thresholds in Monkeys
Anesthesiology, 1975The central nervous system toxicities of etidocaine, bupivacaine, and lidocaine were studied during constant-rate intravenous infusions in rhesus monkeys. Comparison of drug effects was achieved by determining the drug dosages and arterial plasma concentrations that induced electrical seizure activity.
E S, Munson +3 more
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Dexmedetomidine Increases the Cocaine Seizure Threshold in Rats
Anesthesiology, 2002Background Central alpha adrenoceptors have been demonstrated to play an important role in the control of seizure activity; moreover, alpha adrenoceptors have been linked to electroencephalogram changes associated with cocaine. The purpose of this study was to determine if dexmedetomidine, a highly selective alpha -adrenoceptor
Robert A, Whittington +4 more
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Effects of Ammonia on Pentylenetetrazole-Induced Seizure Threshold
Metabolic Brain Disease, 1999The effect of chronic perfusion of ammonia on the seizure threshold against pentylenetetrazol was studied. Ammonia plus sodium bicarbonate and saline (0.9%) was continuously administered to two groups of rats respectively. All animals were tested three times for seizure threshold, and were then decapitated and the brains removed for analysis of the ...
K, Arikan +3 more
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Dihydroergotoxine and the Seizure Threshold.
International pharmacopsychiatry, 1981Dihydroergotoxine administration shortened the latency of allylglycine-and picrotoxin-induced convulsions in rats and increased the incidence of convulsions elicited by picrotoxin, i.e., it lowered ED50 for picrotoxin. The same drug (0.1-10.0 mg/kg) decreased the levels of gamma-aminobutyric acid (GABA) in the caudate nucleus and cingulate cortex, but ...
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Mouse strain variation in maximal electroshock seizure threshold
Brain Research, 2002Maximal electroshock seizure threshold (MEST) is a classical measure of seizure sensitivity with a wide range of experimental applications. We determined MEST in nine inbred mouse strains and one congenic strain using a procedure in which mice are given one shock per day with an incremental (1 mA) current increase in each successive trial until a ...
Thomas N, Ferraro +5 more
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Implications of stimulus factors governing kindled seizure threshold
Experimental Neurology, 1984Seizure threshold was measured in kindled rats by delivering trains of specified duration, consisting of bipolar pulses of specified width, at increasing current intensities, at specified intertrain intervals. The effect of decreasing pulse width was to elevate seizure threshold, but considerably less total energy was required to elicit a seizure ...
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RELATIONSHIP OF PHENYLALANINE TO SEIZURE THRESHOLD DURING MATURATION
Journal of Neurochemistry, 1970Abstract—The effect on seizure threshold of the acute intraperitoneal administration of dl‐phenylalanine in varying doses to the albino rat at different ages was investigated. Seizure threshold was measured by the technique using the volatile convulsant, hexafluorodiethylether.
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Medial septal stimulation increases seizure threshold and improves cognition in epileptic rats
Brain Stimulation, 2019A. Izadi +5 more
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Stimulus Intensity, Seizure Threshold, and Seizure Duration
Psychiatric Clinics of North America, 1991Harold A. Sackeim +2 more
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