Results 101 to 110 of about 352,372 (280)

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

Epilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang, Hong Chen, Xin Ding, Xueyan Cao, Jiahui Mai, Huafang Zou, Dongfang Zou, Yanwei Zhu, Jianxiang Liao, Dezhi Cao   +9 more
wiley   +1 more source

Dexamethasone Attenuates Hyperexcitability Provoked by Experimental Febrile Status Epilepticus. [PDF]

, 2019
The role of neuroinflammation in the mechanisms of epilepsy development is important because inflammatory mediators provide tractable targets for intervention.
Baram, Tallie Z, Chen, Kevin, Dubé, Celine M, Eltom, Nihal, Garcia-Curran, Megan M, Hall, Alicia M, Patterson, Katelin P, Shao, Manlin   +7 more
core   +1 more source

Efficacy and tolerability of fenfluramine with concomitant potassium bromide in patients with Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective To assess the efficacy and tolerability of fenfluramine (FFA) with concomitant potassium bromide (BR) in patients with Dravet syndrome (DS). Methods This multicenter retrospective study, conducted within the German compassionate use program, analyzed BR doses and serum levels before and after FFA initiation, adverse events (AEs ...
Milka Pringsheim, Gerhard Kluger, Adam Strzelczyk, Susanne Schubert‐Bast, Thomas Mayer, Benjamin Glauche, Hiltrud Muhle, Michael Alber, Hartwig Spors, Tilmann Polster, Regina Trollmann, Gerhard Kurlemann, Markus Berndt, Kerstin A. Klotz   +13 more
wiley   +1 more source

Characteristics of Children Admitted to the Emergency Department with Convulsive Epileptic Seizures: A Single-Center Study

Journal of Pediatric Emergency and Intensive Care Medicine, 2017
Introduction: To evaluate the etiology and characteristics of children admitted to the emergency department with an acute convulsive epileptic seizure. Methods: Data of patients who were admitted to the emergency department with a convulsive epileptic ...
Emel Ataş Berksoy, Ünsal Yılmaz, Rana İşgüder, Selçuk Yazıcı, Tanju Çelik, Aycan Ünalp   +5 more
doaj   +1 more source

The assessment of laboratory parameters in children with fever and febrile seizures

Brain and Behavior, 2017
The aim of the research paper was to assess selected laboratory results in children with fever without seizures and febrile seizure.
Krystyna Gontko-Romanowska, Z. Żaba, Paweł Panieński, B. Steinborn, Michał Szemień, Magdalena Łukasik-Głębocka, Krystian Ratajczak, J. Górny   +7 more
semanticscholar   +1 more source

PENYAKIT-PENYAKIT YANG MENYERTAI KEJADIAN KEJANG DEMAM ANAK DI RSUP Dr. KARIADI SEMARANG [PDF]

, 2014
Latar Belakang : Kejang demam dapat dikatagorikan menjadi kejang demam simplek dan kejang demam komplek. Penyakit-penyakit yang menyertai pada kejang demam harus diwaspadai bagi para klinisi karena agar dapat mencegah kerusakan otak yang lebih buruk ...
Nugroho, Wisnu Wahyu, Putranti, Alifiani Hikmah   +1 more
core   +1 more source

Report on advances for pediatricians in 2018: allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroenterology, infectious diseases, neonatology, nutrition, respiratory tract disorders and surgery. [PDF]

, 2019
This review reported notable advances in pediatrics that have been published in 2018. We have highlighted progresses in allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroenterology, infectious diseases, neonatology ...
Bernasconi S, Borrelli M, Caffarelli C, Corsello G., Di Pinto R, Gaeta V, Iovane B, Mastrorilli C, Petraroli M, Santamaria F, Santoro A   +10 more
core   +2 more sources

SCN1A gain of function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications

Epilepsia Open, EarlyView.
Abstract A large number of cases with Dravet syndrome (DS) has been attributed to SCN1A loss of function (LOF), whereas SCN1A gain‐of‐function (GOF) causes early infantile developmental and epileptic encephalopathy (EIDEE) and familial hemiplegic migraine 3.
Yoko Kobayashi Takahashi, Kenshiro Tabata, Shimpei Baba, Eri Takeshita, Noriko Sumitomo, Yuko Shimizu‐Motohashi, Takashi Saito, Eiji Nakagawa, Atsushi Ishii, Shinichi Hirose, Mitsuhiro Kato, Naomichi Matsumoto, Hirofumi Komaki, Ken Inoue   +13 more
wiley   +1 more source

Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures

Journal of Neuroinflammation, 2011
Objective Febrile seizures are the most common form of childhood seizures. Fever is induced by pro-inflammatory cytokines during infection, and pro-inflammatory cytokines may trigger the development of febrile seizures.
Min Hyun Jin, Choi Jieun, Shin Jeon-Soo
doaj   +1 more source

Therapy Management of Simple Febrile Seizure with Hyperpirexia in Three Years Old Child [PDF]

, 2014
Background: Febrile seizures are seizures that occur if body temperature rise more than 380C that caused by a process extracranium in children aged less than 6 years, no evidence of central nervous system infection or acute systemic metabolic disorders ...
Erwika, A. (Asticaliana)
core