Results 121 to 130 of about 40,963 (257)

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Clinical progress note: Rubella

Journal of Hospital Medicine, EarlyView.
Abstract Rates of rubella infection and congenital rubella syndrome decreased significantly since the introduction of the rubella vaccine in 1969. Endemic rubella was declared eliminated in the United States in 2004, and since 2012, all rubella cases in the United States have been associated with infections acquired abroad.
Adam E. Gailani, Walter Dehority, Sophie E. Katz   +2 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Brain damage following whooping cough vaccination : is it time to lay the myth to rest? [PDF]

, 1998
Whooping cough causes significant morbidity and mortality, especially in early infancy. Although an effective vaccine exists, vaccine uptake in Malta was previously disappointing due to the general public’s and the medical community’s doubts regarding ...
Busuttil, Ray, Grech, Victor E.
core  

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source

What are the vector species of the Oropouche virus?

Pest Management Science, EarlyView.
Here, we review the timeline of Oropouche virus (OROV) detection in various hematophagous Diptera, from 1955 to date, including mosquitoes and midges. All vector competence experiments also are described. The results suggest that Culicoides are the primary vectors.
Constância Flávia Junqueira Ayres, Bruna Lais Sena do Nascimento, Daniele Barbosa de Almeida Medeiros, Joaquim Pinto Nunes Neto   +3 more
wiley   +1 more source

Development and validation of a nomogram for the estimation of the prognosis of patients presenting with a febrile seizure

BMC Pediatrics
Background Febrile seizures constitute a prevalent emergency in early childhood. Previous studies indicated that certain febrile seizures in children may progress to epilepsy, exerting a substantial impact on children's health and developmental ...
Qingran Wang, Weiling Sun, Jinyan Zhao, Lili Tong, Baomin Li   +4 more
doaj   +1 more source

Global Emergency Medicine: A Scoping Review of the Literature From 2024

Academic Emergency Medicine, EarlyView.
ABSTRACT Objective The Global Emergency Medicine Literature Review (GEMLR) identifies impactful research in global emergency care. This 20th annual edition reviews GEM literature published in 2024 and highlights the growth of GEMLR over the years. Methods We conducted a scoping review of 2024 GEM articles through structured PubMed and gray literature ...
J. Austin Lee, Nana Serwaa A. Quao, Amanda Collier, Chris A. Rees, Morgan C. Broccoli, Nanaba A. Dawson‐Amoah, Vinay N. Kampalath, Joseph Ciano, Ashley Jacobson, Jennifer Jones, Joseph Leanza, Branden Skarpiak, Jonathan M. Strong, Braden J. Hexom, Global Emergency Medicine Literature Review (GEMLR) Group, Abdirahman Abdulle, Halley J. Alberts, Kimonia Bih Awanchiri, Emily Bartlett, Tal Berkowitz, Nidhi Bhaskar, Corey B. Bills, Joseph Bonney, Morgan C. Broccoli, Agatha Brzezinski, Whitney K. Bryant, Jonathan Chan, Joseph D. Ciano, Cassandra Clay, Ly Cloessner, Amanda Collier, Nanaba A. Dawson‐Amoah, Kamoga Dickson, Jonathan W. Dyal, Christian Engelen, Brandon Friedman, Stephanie Chow Garbern, Juliette Gerardo, Mindi Guptill, Reid Haflich, Alison S. Hayward, Braden J. Hexom, Taylor S. Hickey, Anneka Hooft, Emmanuel Oluyinka Idowu, Ashley A. Jacobson, Aqeel Jawahir, Jennifer E. Jones, Vinay N. Kampalath, Elizabeth M. Keating, Sean M. Kivlehan, Arthi S. Kozhumam, Colleen E. Laurence, Joseph Leanza, Samuel Lewis, J. Austin Lee, Gideon Loevinsohn, Parker Maddox, Mallika Manyapu, Michael Mathelier, Kevin J. Mercer, Rmaah Memon, Kevin Molyneux, Dana Naamani, Benjamin D. Nicholson, Hannah Ofosua Owusu, Gerard M. O’Reilly, Mayur Patel, Nana Serwaa Agyeman Quao, Sarah Rapaport, Chris A. Rees, Charlotte Roy, Megan M. Rybarczyk, Jessica Schmidt, Megan L. Schultz, Anand Selvam, Erin F. Shufflebarger, Yusra Shakil, Branden Skarpiak, Cheyenne Smith, Jonathan M. Strong, Janet Jebichii Sugut, Fadhila Tekka, W. Tyler Winders, Ann Wolski, Natalie Yabalwashi   +85 more
wiley   +1 more source

“Systematic review of HHV-6 and febrile seizures: Should the ER include it in the viral panel?”

Journal of Clinical Virology Plus
Background: Human herpesvirus 6 (HHV-6), particularly subtype B, is a common viral infection in childhood and the cause of roseola infantum. Beyond its dermatologic effects, HHV-6B is an important yet often underrecognized contributor to febrile seizures
Shaina Gagadam, Valerie Foy
doaj   +1 more source

Rare Coinfection of Scrub Typhus and Malaria in Immunocompetent Person [PDF]

, 2012
Scrub Typhus, or tsutsugamushi disease is a febrile illness caused by bacteria of the family Rickettsiaceae and named Orientia tsutsugamushi. Recently it has been found to endemic in Subhimalayan region of India.Malaria is highly endemic in rest of India
Bellad, A, Dhiman, P, Madhabhavi, I, Panda, P, Raina, R, Sharma, A   +5 more
core   +1 more source