Results 131 to 140 of about 22,409 (239)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Acute Fulminant Cerebral Edema Caused by Coxsackievirus A6 Infection: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT In recent years, Coxsackievirus A6 (CV‐A6) has gradually replaced Enterovirus 71 (EV‐71) and Coxsackievirus A16 (CV‐A16) as the main pathogen causing hand foot mouth disease (HFMD) in China. This article reports a fatal case of HFMD caused by CV‐A6, leading to fulminant cerebral edema and cardiopulmonary arrest.
Kang An, Juan Qian
wiley   +1 more source

The Real‐World Safety Profile of Temazepam: A 20‐Year Pharmacovigilance Analysis Based on the Large‐Scale FAERS Database

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
This study aimed to comprehensively characterize temazepam's safety profile by a large‐scale analysis of real‐world data. Most adverse events occur within the first 30 days of treatment. The findings highlighted the need for enhanced clinical vigilance and dynamic.
Zujun Wen, Xiang Liu, Peng Liu
wiley   +1 more source

Advantages of Exome Sequencing Over Panel Testing for Individuals With a Seizure Indication

open access: yesAnnals of the Child Neurology Society, Volume 4, Issue 1, Page 29-37, March 2026.
ABSTRACT Objective Our aim was to investigate the advantages of exome sequencing versus panel testing for patients with unexplained seizures. Methods We reviewed the diagnostic outcomes of exome sequencing by a commercial genetics laboratory for more than 16 000 individuals with a clinical history of seizures or suspected seizures.
Michelle M. Morrow   +8 more
wiley   +1 more source

Epilepsy Phenotypic Spectrum of NUS1‐Related Disorder: A Case Series

open access: yesAnnals of the Child Neurology Society, Volume 4, Issue 1, Page 95-100, March 2026.
ABSTRACT Background Epilepsy with myoclonic and atonic seizures (EMAtS), also known as Doose syndrome, accounts for 1%–2% of childhood epilepsies, and various genes have been implicated in causing this epilepsy syndrome. NUS1 encodes for Nogo‐B receptor (NgBR), which stabilizes the dehydrodolichyl‐diphosphate synthase complex in the endoplasmic ...
Saumel Ahmadi   +6 more
wiley   +1 more source

Beyond the seizure: the role of post-event observation in febrile seizure management. [PDF]

open access: yesEur J Pediatr
Test G   +9 more
europepmc   +1 more source

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