Results 161 to 170 of about 352,372 (280)

Trends in Paediatric Viral Meningitis and Encephalitis With Unconfirmed Aetiology: A Spanish Population‐Based Study, 2016–2020

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The prevalence of meningitis and encephalitis of unknown aetiology in Spanish children has not been specifically documented before. The aim of this study is to describe the epidemiology and trends of these clinical conditions between 2016 and 2020.
Marina Pons‐Espinal   +5 more
wiley   +1 more source

Cannabinoids for Medical Purposes in Children: A Living Systematic Review

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim We developed a living systematic review (LSR) that will continuously map the safety and reported benefit data related to cannabinoid use for medical purposes in children. Methods MEDLINE, Embase, PsycInfo, and the Cochrane Library were searched from inception to April 2023.
Manik Chhabra   +7 more
wiley   +1 more source

Accuracy of Inflammatory Biomarkers for Ruling out Invasive Bacterial Infections in Young Febrile Infants

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To investigate the diagnostic accuracy of procalcitonin (PCT), C‐reactive protein (CRP) and absolute neutrophil count (ANC) to rule out invasive bacterial infections (IBI) in well‐appearing febrile infants aged ≤ 60 days. Methods Multicentre study of infants ≤ 60 days with fever without source.
Ebba Nordström Carlsson   +2 more
wiley   +1 more source

The Chilean Revolts and the Failure of the Constituent Process

open access: yesBulletin of Latin American Research, EarlyView.
This article aims to contextualise the recent constituent process in Chile and its subsequent failure, paying attention not only to the so‐called contingent nature of the revolts inaugurated in October 2019, but also to the reengineering process implemented by the Pinochet dictatorship.
Sergio Villalobos‐Ruminott
wiley   +1 more source

Combined screening of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus in an emergency department: The URDEPTRIO cross‐sectional study

open access: yes
Academic Emergency Medicine, EarlyView.
Chris Wong   +14 more
wiley   +1 more source

The risk of epilepsy after neonatal seizures

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16288 Abstract Aim To estimate the cumulative risk of epilepsy after neonatal seizures and identify subpopulations at increased risk. Method This was a nationwide register‐based cohort study including all children born in Denmark between 1997 and 2018.
Jeanette Tinggaard   +6 more
wiley   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment. The pathogenesis of these lesions encompasses a range of causes, including haemorrhagic, embolic, or other vascular events; exposure to teratogens, such as drugs or substance
Ana Alarcón   +33 more
wiley   +1 more source

Sensitization of Non‐M3 Acute Myeloid Leukemia Blasts to All‐Trans Retinoic Acid by the LSD1 Inhibitor Tranylcypromine: TRANSATRA Phase I Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski   +22 more
wiley   +1 more source

Community‐onset pediatric status epilepticus: Barriers to care and outcomes in a real‐world setting

open access: yesEpilepsia, Volume 66, Issue 3, Page 725-738, March 2025.
Abstract Objective Status epilepticus (SE) is a neurological emergency in childhood, often leading to neuronal damage and long‐term outcomes. The study aims to identify barriers in the pre‐hospital and in‐hospital management of community‐onset pediatric SE and to evaluate the effectiveness of pediatric scores on outcomes prediction.
Anna Fetta   +12 more
wiley   +1 more source

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