Results 101 to 110 of about 615,127 (352)

Postencephalitic epilepsy in dogs with meningoencephalitis of unknown origin: Clinical features, risk factors, and long‐term outcome

Journal of Veterinary Internal Medicine, 2020
Background Although the presence of seizures in dogs with meningoencephalitis of unknown origin (MUO) has been associated with shorter survival times, data regarding the prevalence and risk factors for postencephalitic epilepsy (PEE) is lacking ...
Adriana Kaczmarska, Roberto José‐López, Michał Czopowicz, Kali Lazzerini, Guillaume Leblond, Catherine Stalin, Rodrigo Gutierrez‐Quintana   +6 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy. [PDF]

, 1996
Lina Nashef, F Walker, Penny Allen, Josemir W. Sander, Simon Shorvon, D. R. Fish   +5 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Case Report: Cerebral folate deficiency caused by FOLR1 variant

Frontiers in Pediatrics
BackgroundCerebral folate transport deficiency (CFD) is a rare neurological disease characterized by a deficiency in 5-methyltetrahydrofolate (5-MTHF) in the cerebrospinal fluid, with a normal peripheral total folate level.
Qian Wang, Qian Wang, Jie Yang, Jie Yang, Chunmei Yu, Chunmei Yu, Yao Deng, Yao Deng, Qianhui Wen, Qianhui Wen, Hua Yang, Hua Yang, Hao Liu, Hao Liu, Rong Luo, Rong Luo   +15 more
doaj   +1 more source

Automatic Diagnosis of Epileptic Seizure in Electroencephalography Signals Using Nonlinear Dynamics Features [PDF]

, 2019
Shanen Chen, Xi Zhang, Lili Chen, Zhixian Yang   +3 more
openalex   +1 more source

A longitudinal seizure outcome following the COVID-19 pandemic in 2020 and 2021: Transient exacerbation or sustainable mitigation [PDF]

, 2021
Shuichiro Neshige, Shiro Aoki, Yoshiko Takebayashi, Takeo Shishido, Yu Yamazaki, Koji Iida, Hirofumi Maruyama   +6 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Investigating the Anti-epileptic and Sedative Effects of Hydroalcoholic Extract of Melissa officinalis (Lemon Balm) Leaf on Pentylenetetrazol Induced Epileptiform Seizures in Wistar Rat

Journal of Medicinal Plants, 2012
Background: Since long lasting administration of anti-seizure drugs produces undesirable side effects, many efforts have been made during recent decades to find and replace the chemical drugs by medicinal plants.
MB Ghayour, M Behnam-Rassouli, N Ghayour, M Tehranipour, A Kamyabi-Abkooh   +4 more
doaj  

A survey of relative frequency of etiologies, time of onset, efficacy of drug therapy and risk factors for clinical neonatal seizures [PDF]

Introduction: Seizure is a common condition in neonatal period and may become first feature of neurologic dysfunction. In most cases, diagnosis of neonatal seizure and its different etiologies are based on history, clinical manifestations and ...
براک, منوچهر, معماری, احد, میرزا رحیمی, مهرداد, پوستی, علیرضا   +3 more
core