Results 111 to 120 of about 615,127 (352)

Dose-dependent seizure control with MEK inhibitor therapy for progressive glioma in a child with neurofibromatosis type 1 [PDF]

, 2022
Evan Cantor, Ashley Meyer, Stephanie M. Morris, Judith Weisenberg, Nicole M Brossier   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Loss of TrkB Signaling Due to Status Epilepticus Induces a proBDNF-Dependent Cell Death

Frontiers in Cellular Neuroscience, 2019
Neurotrophins (NTs) are secretory proteins that bind to target receptors and influence many cellular functions, such as cell survival and cell death in neurons.
Laura Ester Montroull, Víctor Danelon, Andrea Beatriz Cragnolini, Daniel Hugo Mascó   +3 more
doaj   +1 more source

Cerebral function monitoring in term or near term neonates at MDH : preliminary experience and proposal of a guideline [PDF]

, 2012
Introduction: Cerebral function monitoring (CFM) is a simplified EEG device that is used to monitor cerebral function at the cot-side. Various studies have shown its value in detecting neonatal encephalopathy and electrographic seizures, prognostication ...
Attard, Stephen, Soler, Doriette, Soler, Paul   +2 more
core  

Hypermobility in patients with functional seizures: Toward a pathobiological understanding of complex conditions [PDF]

, 2022
Akihiro Koreki, Jessica Eccles, Sarah N. Garfinkel, Hugo Critchley, Sarah Cope, Niruj Agrawal, Mark J. Edwards, Mahinda Yogarajah   +7 more
openalex   +1 more source

Nonepileptic Seizures

Neurologic Clinics, 1995
The widespread use of video-electroencephalogram monitoring has dramatically increased our recognition of the high prevalence and diversity of nonepileptic seizures. Nonepileptic seizures stand squarely in the interface between psychiatry and neurology, an area that has been both claimed and denied by both sides.
O, Devinsky, K, Thacker
openaire   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

GABA_A Receptors Are Involved in the Seizure Blockage Prompted by a Polyphenol-Rich Extract of White Grape Juice in Rodents

Pharmaceuticals
Background/Objectives: Polyphenols have been suggested to possess anticonvulsant properties, which can be exploited as tools in novel strategies against epilepsy.
Alessandro Maugeri, Rita Citraro, Antonio Leo, Caterina Russo, Michele Navarra, Giovambattista De Sarro   +5 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

No evidence for critical slowing down prior to human epileptic seizures [PDF]

, 2019
Theresa Wilkat, Thorsten Rings, Klaus Lehnertz   +2 more
openalex   +1 more source