Results 141 to 150 of about 307,198 (323)

Dyke‐Davidoff‐Masson syndrome—A rare cause of recurrent seizures in adulthood

Clinical Case Reports
Key Clinical Message It is important to consider DDMS as a differential diagnosis in any patient with early childhood onset of epilepsy. Early diagnosis and optimal management are key to reducing the disabling effect of DDMS.
Patricia Afrim, Emmanuel Ofori, Nana Akosua Owusu‐Danso, Rexford Adu Gyamfi, Denise Akua Owusua, Solomon Gyabaah, Fred Stephen Sarfo   +6 more
doaj   +1 more source

On Epilepsy and Epileptiform Seizures, their Causes, Pathology, and Treatment [PDF]

D F C
openalex   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Spatio-Temporal Correlation of Epileptic Seizures with The Electrocardiography Brain Perfusion Index [PDF]

arXiv
The Electrocardiography Brain Perfusion index (EBPi) is a novel electrocardiography (ECG)-based metric that may function as a proxy for cerebral blood flow (CBF). We investigated the spatio-temporal correlation between EBPi and epileptic seizure events.
arxiv  

Epilepsy in rural South Africa: Patient experiences and healthcare challenges

Epilepsia Open
Objective This study investigates the prevalent issues of healthcare access and the impact of antiseizure treatments among people with epilepsy (PWE) in rural Limpopo and Mpumalanga, South Africa, where healthcare facilities and affordable treatments are
Lufuno Makhado, Angelina Maphula, Richard Teke Ngomba, Ofhani Prudance Musekwa, Thendo Gertie Makhado, Muofheni Nemathaga, Mukovhe Rammela, Muimeleli Munyadziwa, Pasquale Striano   +8 more
doaj   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

The significance of multimodality approach in the management of non‐lesional drug‐resistant focal parietal lobe epilepsies

Epilepsia Open
Due to extensive connectivity of the parietal lobe, non‐lesional drug‐resistant (DRE) parietal lobe epilepsies (PLEs) are difficult to localize and often imitate other epilepsies.
Patrick Hartnett, Naseem Zomorodi, Howard P. Goodkin, Ifrah Zawar   +3 more
doaj   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Juvenile idiopathic epilepsy in Egyptian Arabian foals, a potential animal model of self‐limited epilepsy in children

Journal of Veterinary Internal Medicine
Background Juvenile idiopathic epilepsy (JIE) is categorized as a generalized epilepsy. Epilepsy classification entails electrocortical characterization and localization of epileptic discharges (ED) using electroencephalography (EEG).
Monica Aleman, Ruba Benini, Sami Elestwani, Tatiana Vinardell   +3 more
doaj   +1 more source

A GROUP OF COMPOUNDS POSSESSING ANTICONVULSANT ACTIVITY IN THE MAXIMAL ELECTROSHOCK SEIZURE TEST

, 1957
Kiyoshi Tanaka, YOSUKE KAWASAKI
openalex   +1 more source