Results 201 to 210 of about 809,992 (403)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Epilepsy in rural South Africa: Patient experiences and healthcare challenges

Epilepsia Open
Objective This study investigates the prevalent issues of healthcare access and the impact of antiseizure treatments among people with epilepsy (PWE) in rural Limpopo and Mpumalanga, South Africa, where healthcare facilities and affordable treatments are
Lufuno Makhado, Angelina Maphula, Richard Teke Ngomba, Ofhani Prudance Musekwa, Thendo Gertie Makhado, Muofheni Nemathaga, Mukovhe Rammela, Muimeleli Munyadziwa, Pasquale Striano   +8 more
doaj   +1 more source

Spatio-Temporal Correlation of Epileptic Seizures with The Electrocardiography Brain Perfusion Index [PDF]

arXiv
The Electrocardiography Brain Perfusion index (EBPi) is a novel electrocardiography (ECG)-based metric that may function as a proxy for cerebral blood flow (CBF). We investigated the spatio-temporal correlation between EBPi and epileptic seizure events.
arxiv  

A method of analysis of seizure pattern and electroencephalogram A cinematographic technique

, 1949
John D. Hunter, Herbert H. Jasper
openalex   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source

The significance of multimodality approach in the management of non‐lesional drug‐resistant focal parietal lobe epilepsies

Epilepsia Open
Due to extensive connectivity of the parietal lobe, non‐lesional drug‐resistant (DRE) parietal lobe epilepsies (PLEs) are difficult to localize and often imitate other epilepsies.
Patrick Hartnett, Naseem Zomorodi, Howard P. Goodkin, Ifrah Zawar   +3 more
doaj   +1 more source

Seizures induced by movement: report of a case relieved by operation [PDF]

, 1963
M. A. Falconer, M. V. Driver, E. A. Serafetinides   +2 more
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Juvenile idiopathic epilepsy in Egyptian Arabian foals, a potential animal model of self‐limited epilepsy in children

Journal of Veterinary Internal Medicine
Background Juvenile idiopathic epilepsy (JIE) is categorized as a generalized epilepsy. Epilepsy classification entails electrocortical characterization and localization of epileptic discharges (ED) using electroencephalography (EEG).
Monica Aleman, Ruba Benini, Sami Elestwani, Tatiana Vinardell   +3 more
doaj   +1 more source

A survey of relative frequency of etiologies, time of onset, efficacy of drug therapy and risk factors for clinical neonatal seizures [PDF]

Introduction: Seizure is a common condition in neonatal period and may become first feature of neurologic dysfunction. In most cases, diagnosis of neonatal seizure and its different etiologies are based on history, clinical manifestations and ...
براک, منوچهر, معماری, احد, میرزا رحیمی, مهرداد, پوستی, علیرضا   +3 more
core