Results 41 to 50 of about 474,180 (232)

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits. [PDF]

, 2017
The calcium-binding protein calbindin-D28k is critical for hippocampal function and cognition, but its expression is markedly decreased in various neurological disorders associated with epileptiform activity and seizures.
Chin, Jeannie, Corbett, Brian F., LaFrancois, John J., Mohila, Carrie A., Muralidharan, Kavitha, Nestler, Eric J., Park, Jin W., Petrof, Iraklis, Pyfer, Mark S., Rissman, Robert A., Scharfman, Helen E., Yoshor, Daniel, You, Jason C., Zhang, Xiaohong, Zheng, Yi   +14 more
core   +1 more source

SEIZURES WITH ANTI-SEIZURE DRUG

Asian Journal of Pharmaceutical and Clinical Research, 2017
This case study is to report and explore the etiology of a case of refractory seizures due to overdosage of phenytoin tablets. A case report from the Department of Neurology generated through voluntary adverse drug reaction (ADR)reporting stated phenytoin overdosage leading to refractory status epilepticus which did not respond to any of the ...
Bhuvaneshwari K, Keerthana Brattiya
openaire   +3 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

The Insula and Its Epilepsies [PDF]

, 2019
Insular seizures are great mimickers of seizures originating elsewhere in the brain. The insula is a highly connected brain structure. Seizures may only become clinically evident after ictal activity propagates out of the insula with semiology that ...
Gonzalez-Martinez, Jorge, Isnard, Jean, Jobst, Barbara C., Kahane, Philippe, Lacuey, Nuria, Lado, Fred, Lahtoo, Samden D., Nguyen, Dang K., Wu, Chengyuan   +8 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Inhomogeneous cortical synchronization and partial epileptic seizures [PDF]

, 2014
Objective: Interictal synchronization clusters have recently been described in several publications using diverse techniques, including neurophysiological recordings and fMRI, in patients suffering from epilepsy.
García de Sola, Rafael, Ortega, Guillermo José, Pastor, Jesús Eduardo, Vega Zelaya, Lorena   +3 more
core   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

International Veterinary Epilepsy Task Force Consensus Proposal: Diagnostic approach to epilepsy in dogs [PDF]

, 2015
This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research ...
A Pákozdy, Akos Pakozdy, Andrea Fischer, Andrea Tipold, AT Berg, BG Licht, C Brauer, C Brauer, CL Mariani, Clare Rusbridge, EE Patterson, EE Patterson, G Urkasemsin, Heidrun Potschka, Holger A. Volk, J Guevar, Jacques Penderis, JJ Lin, JL Gill, JW Schmidley, Karen Muñana, Kaspar Matiasek, KJ Ekenstedt, L Arrol, LM Mellema, Luisa De Risio, M Armaşu, M Berendt, M Podell, M Schwartz, M Schwartz, M Wolf, Martí Pumarola Batlle, Mette Berendt, Michael Podell, N Shihab, Ned Patterson, O Devinsky, Paul JJ. Mandigers, PM Smith, R Edwards, R Erro, R Gonçalves, R Poma, R Zimmermann, RMA Packer, Robyn Farqhuar, Rowena MA Packer, RS Fisher, RS Fisher, S Shorvon, Sam Long, Simon Platt, Sofie Bhatti, TM Ghormle, V Hülsmeyer, Veronika Stein, WB Thomas, WW Bush, YC Huang   +59 more
core   +8 more sources