Results 51 to 60 of about 615,127 (352)
Neuropsychiatric Disease and Treatment, 2023 Ana Paula Mafla-Mendoza,1,* Esteban David Paredes-Urbano,1,* Enrique Gea-Izquierdo1– 3 1Pontifical Catholic University of Ecuador, Faculty of Medicine, Quito, Ecuador; 2Department of Medical Specialties and Public Health, Rey Juan Carlos ...
Mafla-Mendoza AP +2 more
doaj
p53-sensitive epileptic behavior and inflammation in Ft1 hypomorphic mice [PDF]
, 2018 Epilepsy is a complex clinical condition characterized by repeated spontaneous seizures. Seizures have been linked to multiple drivers including DNA damage accumulation.
Alessandro, Vercelli +10 more
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Insula and Its Epilepsies [PDF]
, 2019 Insular seizures are great mimickers of seizures originating elsewhere in the brain. The insula is a highly connected brain structure. Seizures may only become clinically evident after ictal activity propagates out of the insula with semiology that ...
Gonzalez-Martinez, Jorge +8 more
core +1 more source
Seizure characterisation using frequency-dependent multivariate dynamics [PDF]
, 2009 The characterisation of epileptic seizures assists in the design of targeted pharmaceutical seizure prevention techniques and pre-surgical evaluations.
Adeli +31 more
core +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Nitric Oxide Regulates Neurogenesis in the Hippocampus following Seizures [PDF]
, 2015 Hippocampal neurogenesis is changed by brain injury. When neuroinflammation accompanies injury, activation of resident microglial cells promotes the release of inflammatory cytokines and reactive oxygen/nitrogen species like nitric oxide (NO).
Araújo, Inês +4 more
core +4 more sources
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Temporal lobe hypogenesis associated with arachnoid cyst in patients with epilepsy [PDF]
Arquivos de Neuro-Psiquiatria, 2003 OBJECTIVE: To determine the frequency of temporal lobe hypogenesis (TLH) associated with arachnoid cysts (AC) in patients with epilepsy. METHOD: We retrospectively revised 655 consecutive MRI scans from patients followed in our epilepsy clinic.
Eliane Kobayashi +3 more
doaj +1 more source