Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Synchronization Implies Seizure or Seizure Implies Synchronization? [PDF]
Epileptic seizures are considered as abnormally hypersynchronous neuronal activities of the brain. Do hypersynchronous neuronal activities in a brain region lead to seizure or the hypersynchronous activities take place due to the progression of the seizure? We have examined the ECoG signals of 21 epileptic patients consisting of 87 focal-onset seizures
arxiv
Self-Supervised Graph Neural Networks for Improved Electroencephalographic Seizure Analysis [PDF]
Automated seizure detection and classification from electroencephalography (EEG) can greatly improve seizure diagnosis and treatment. However, several modeling challenges remain unaddressed in prior automated seizure detection and classification studies: (1) representing non-Euclidean data structure in EEGs, (2) accurately classifying rare seizure ...
arxiv
Comparison of Clinical Characteristics in Patients with Febrile Seizures Based on Prior COVID-19 Infection [PDF]
Purpose Febrile seizures (FSs) are neurological events associated with fever, typically occurring in children between 6 months and 5 years of age in the absence of central nervous system infection. Growing evidence suggests that coronavirus disease 2019 (
Su-Jeong You
doaj +1 more source
Investigators in the sections of Neurophysiology and Pediatric Neurology, Baylor College of Medicine, Houston, TX, have characterized and classified 415 clinical seizures recorded in 71 neonates and 11 with EEG seizure activity without clinical accompaniments.
openaire +7 more sources
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Six-center Assessment of CNN-Transformer with Belief Matching Loss for Patient-independent Seizure Detection in EEG [PDF]
Neurologists typically identify epileptic seizures from electroencephalograms (EEGs) by visual inspection. This process is often time-consuming, especially for EEG recordings that last hours or days. To expedite the process, a reliable, automated, and patient-independent seizure detector is essential.
arxiv
An Interesting Case Series of Neuropsychiatric Lupus: A Combination of Inflammatory and Thrombotic Origin [PDF]
Systemic Lupus Erythematosus (SLE) is a versatile autoimmune disorder with multisystem organ involvement, most commonly involving the skin, joints, vasculature, and associated immunological abnormalities.
Rajkumar Kannan+3 more
doaj +1 more source
Glial neoplasms account for nearly 50% of all adult primary brain tumors. They originate from glial cells in the brain and/or spinal cord and include low-grade diffuse astrocytomas, anaplastic-astrocytomas, and glioblastomas. Of all brain tumors, glioblastoma multiforme (GBM) is the most aggressive and is characterized by rapid glial cell growth ...
Alberto E. Musto+4 more
openaire +3 more sources